background: the aim of this study is to determine the frequency of intracranial artery stenosis in patients with acute ischemic stroke in iran. methods: a total of 169 patients with acute ischemic stroke were eligible to participate and were enrolled in this study from january 2012 to february 2013. all the patients were admitted to the nemazee ‎hospital, affiliated to shiraz university of medi...

Abstract Background: Transcranial Doppler ultrasonography results have not been previously studied in among Iranian sickle cell anemia patients. The present study was performed to evaluate the pattern of intracranial flow velocities among Iranian children with sickle cell anemia and the hematological parameters that can affect the time-averaged mean of maximum velocity in major intracranial...

abstract background: transcranial doppler ultrasonography results have not been previously studied in among iranian sickle cell anemia patients. the present study was performed to evaluate the pattern of intracranial flow velocities among iranian children with sickle cell anemia and the hematological parameters that can affect the time-averaged mean of maximum velocity in major intracranial art...

BACKGROUND AND PURPOSE Atherosclerosis occurs later and is less extensive in intracranial arteries than in extracranial arteries. However, the mechanisms responsible are poorly understood. A previous study has suggested a better antioxidant protection of intracranial arteries. METHODS To assess the influence of age on arterial activity of antioxidant enzymes and atherogenesis, we compared int...

BACKGROUND Atherosclerotic lesions in intracranial arteries occur later and are less extensive than in extracranial arteries. To investigate potential mechanisms responsible for this difference, in particular the atherogenic response to hypercholesterolemia and LDL oxidation, we compared the extent of fatty streak formation and the composition of these very early lesions in intracranial arterie...

Two main vascular routes supply the brain, internal carotid arteries (ICAs) and vertebral arteries. The external artery (ECA) mainly supplies skin, muscle, skull; thus, neurointerventionalists should be aware of ECA‐ICA, ECA‐vertebral artery, extracranial–intracranial anastomoses. These anastomoses are not newly formed but that remnants developmental processes. During development, ICA has with ...

Introduction: Concurrent atherosclerosis of the intracranial and extracranial cerebrovascular system is common in Asians . Atherosclerotic diseases occurring in carotid arteries and intracranial arteries have been demonstrated to be associated transient ischemic attack (TIA) and stroke . Recently, Black-blood magnetic resonance imaging (MRI) has been increasingly applied for assessment of the c...

M ost reported arterial dissections involve the carotid and vertebral arteries in the neck. Within the intracranial arteries, dissections most often involve the vertebral and basilar arteries. Intracranial carotid and middle cerebral artery dissections occur much more rarely and seem to develop in younger individuals compared with patients who develop posterior-circulation intracranial dissecti...

Inflammation plays a key role in formation and rupture of intracranial aneurysms. Because hepatocyte growth factor (HGF) protects against vascular inflammation, we sought to assess the role of endogenous HGF in the pathogenesis of intracranial aneurysms. Circulating HGF concentrations in blood samples drawn from the lumen of human intracranial aneurysms or femoral arteries were compared in 16 p...

BACKGROUND AND PURPOSE Few data are available on the frequency and location distribution of fenestrations of intracranial arteries. We used 3D rotational angiography of all intracranial arteries in a cohort of 179 patients with suspected intracranial aneurysms to assess the prevalence and location of fenestrations and the relation of fenestrations to aneurysms. MATERIALS AND METHODS Of 179 pa...