oxyntomodulin (oxm), a proglucagon-derived peptide, is a well known anorexigenic peptide found inthe gut and brain of mammals. the present study was carried out to investigate the central effect of oxm onfood intake in non-fasted and fasted ross broiler chicks. at four weeks of age, a guide cannula wasstereotaxically implanted into the right lateral ventricle of each bird. two experiments were ...

We determined the cardiovascular and neurohormonal responses to intracerebroventricular injection of leptin in conscious rabbits. Intracerebroventricular injection of leptin elicited dose-related increases in mean arterial pressure and renal sympathetic nerve activity while producing no consistent, significant increases in heart rate. Peak values of mean arterial pressure and renal sympathetic ...

Matsumura, Kiyoshi, Isao Abe, Takuya Tsuchihashi, and Masatoshi Fujishima. Central effects of leptin on cardiovascular and neurohormonal responses in conscious rabbits. Am J Physiol Regulatory Integrative Comp Physiol 278: R1314–R1320, 2000.—We determined the cardiovascular and neurohormonal responses to intracerebroventricular injection of leptin in conscious rabbits. Intracerebroventricular i...

We determined the cardiovascular and neurohormonal responses to intracerebroventricular administration of orexin-A in conscious rabbits. Intracerebroventricular injection of orexin-A elicited dose-related increases in mean arterial pressure and renal sympathetic nerve activity. Peak values of mean arterial pressure and renal sympathetic nerve activity induced by intracerebroventricular injectio...

We determined cardiovascular and neurohormonal responses to intracerebroventricular administration of human cocaine- and amphetamine-regulated transcript (CART) peptide 55-102 in conscious rabbits. Intracerebroventricular injection of CART 55-102 elicited dose-related increases in mean arterial pressure and renal sympathetic nerve activity. Peak values of mean arterial pressure and renal sympat...

We determined cardiovascular and neurohormonal responses to intracerebroventricular administration of human cocaineand amphetamine-regulated transcript (CART) peptide 55 102 in conscious rabbits. Intracerebroventricular injection of CART 55 102 elicited dose-related increases in mean arterial pressure and renal sympathetic nerve activity. Peak values of mean arterial pressure and renal sympathe...

The effects of leumorphin, a kappa-agonist derived from proenkephalin B (neoendorphin and dynorphin precursor), on vasopressin secretion were studied under basal and stimulated conditions in conscious, unrestrained rats. Intracerebroventricular injection of leumorphin (60 or 600 pmol) significantly inhibited basal vasopressin secretion. The vasopressin response induced by intracerebroventricula...

the effect of intracerebroventricular injections of prostaglandins e2 and f2a was studied on the rectal temperature of sheep. pge2 but not pgf2a at the same dose of 50mg elevated the 1h post-injection of rectal temperature. pge2 but not pgf2a at the same dose of 100mg increased 3.5 and 2h post-injection of rectal temperature, respectively. elavation of rectal temperature following pge2 and pgf2...

Rats have an attenuated febrile response to intracerebroventricular injection of PGE1 near the term of pregnancy, the mechanism of which is unknown. The present experiments were carried out to test the hypothesis that arginine vasopressin (AVP), functioning as an endogenous antipyretic substance in the central nervous system, mediates this attenuated febrile response. The febrile response to in...

Fentanyl citrate analgesia attenuates the excess nitrogen excretion in the urine and glucose production induced by trauma. On the other hand, intracerebroventricular injection of morphine stimulates excretion of stress hormones, such as catecholamines and corticosterone. Furthermore, morphine levels in the brain are increased during fasting and sepsis. The aims of this study were to determine w...