نتایج جستجو برای: intestinal flora

تعداد نتایج: 149612  

Journal: :Molecules 2013
Jing Zhou Yan Chen Ying Wang Xia Gao Ding Qu Congyan Liu

The aim of this study was to compare the significance of the intestinal hydrolysis of prenylated flavonoids in Herba Epimedii by an intestinal enzyme and flora. Flavonoids were incubated at 37 °C with rat intestinal enzyme and intestinal flora. HPLC-UV was used to calculate the metabolic rates of the parent drug in the incubation and LC/MS/MS was used to determine the chemical structures of met...

Journal: :Archives of endocrinology and metabolism 2015
Daniela M Tsukumo Bruno M Carvalho Marco A Carvalho Filho Mário J A Saad

Obesity is currently a pandemic of worldwide proportions affecting millions of people. Recent studies have proposed the hypothesis that mechanisms not directly related to the human genome could be involved in the genesis of obesity, due to the fact that, when a population undergoes the same nutritional stress, not all individuals present weight gain related to the diet or become hyperglycemic. ...

2014
Ruijun Wang Guisheng Zhou Mengyue Wang Ying Peng Xiaobo Li

An active polysaccharide from the rhizome of Atractylodes macrocephala Koidz (PAM) was identified to improve and adjust disordered intestinal flora. High-performance gel permeation chromatography (HPGPC) and gas chromatography-mass spectrometry (GC-MS) were employed to identify the components of PAM as rhamnose, glucose, mannose, xylose, and galactose at a ratio of 0.03 : 0.25 : 0.15 : 0.41 : 0...

2011
Esi S. Lamousé-Smith Alice Tzeng Michael N. Starnbach

The presence of a complex and diverse intestinal flora is functionally important for regulating intestinal mucosal immune responses. However, the extent to which a balanced intestinal flora regulates systemic immune responses is still being defined. In order to specifically examine whether the acquisition of a less complex flora influences responses to immunization in the pre-weaning stages of ...

2017
Masanori Horie Takamasa Miura Satomi Hirakata Akira Hosoyama Sakiko Sugino Aya Umeno Kazutoshi Murotomi Yasukazu Yoshida Taisuke Koike

A relationship between type 2 diabetes mellitus (T2DM) and intestinal flora has been suggested since development of analysis technology for intestinal flora. An animal model of T2DM is important for investigation of T2DM. Although there are some animal models of T2DM, a comparison of the intestinal flora of healthy animals with that of T2DM animals has not yet been reported. The intestinal flor...

2018
Shuwen Han Jianlan Gao Qing Zhou Shanshan Liu Caixia Wen Xi Yang

Colorectal cancer is one of the most common human malignant tumors. Recent research has shown that colorectal cancer is a dysbacteriosis-induced disease; however, the role of intestinal bacteria in colorectal cancer is unclear. This review explores the role of intestinal flora in colorectal cancer. In total, 57 articles were included after identification and screening. The pertinent literature ...

2017
Xiai Yang Liangliang Liu Jing Chen Aiping Xiao

In order to investigate the influence of aflatoxin B1 (AFB1) on intestinal bacterial flora, 24 Kunming mice (KM mice) were randomly placed into four groups, which were labeled as control, low-dose, medium-dose, and high-dose groups. They were fed intragastrically with 0.4 mL of 0 mg/L, 2.5 mg/L, 4 mg/L, or 10 mg/L of AFB1 solutions, twice a day for 2 months. The hypervariable region V3 + V4 on ...

2012
Robert R. Jenq Carles Ubeda Ying Taur Clarissa C. Menezes Raya Khanin Jarrod A. Dudakov Chen Liu Mallory L. West Natalie V. Singer Michele J. Equinda Asia Gobourne Lauren Lipuma Lauren F. Young Odette M. Smith Arnab Ghosh Alan M. Hanash Jenna D. Goldberg Kazutoshi Aoyama Bruce R. Blazar Eric G. Pamer Marcel R.M. van den Brink

Despite a growing understanding of the link between intestinal inflammation and resident gut microbes, longitudinal studies of human flora before initial onset of intestinal inflammation have not been reported. Here, we demonstrate in murine and human recipients of allogeneic bone marrow transplantation (BMT) that intestinal inflammation secondary to graft-versus-host disease (GVHD) is associat...

Journal: :World journal of gastroenterology 2005
Alexander Swidsinski Vera Loening-Baucke Herbert Lochs Laura-P Hale

AIM To study the role of intestinal flora in inflammatory bowel disease (IBD). METHODS The spatial organization of intestinal flora was investigated in normal mice and in two models of murine colitis using fluorescence in situ hybridization. RESULTS The murine small intestine was nearly bacteria-free. The normal colonic flora was organized in three distinct compartments (crypt, interlaced, ...

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