نتایج جستجو برای: intestinal aganglionic
تعداد نتایج: 131704 فیلتر نتایج به سال:
Objective(s) Definite diagnosis of Hirschsprung’s disease (HD) is based on histopathological study, but there are limitations associated with standard histology and histochemistry in this regard. The aim of this study was to investigate calretinin immunostaining patterns in both ganglionic and aganglionic HD intestinal specimens and to compare them with control specimens. Materials and Method...
to access the surgical progress of patients with long segment aganglionosis and long-term evaluation. during the past 15 years, we reviewed the therapy and outcome of 15 patients with long-segment agangelionosis (lsa) in mofid children's hospital. 2 with agangelionosis to the midtransvers colon (mta(, 8 to the ascendant and cecum (a/ca), 4 with total colonic and distal ileum involvement (tca), ...
objective(s) definite diagnosis of hirschsprung’s disease (hd) is based on histopathological study, but there are limitations associated with standard histology and histochemistry in this regard. the aim of this study was to investigate calretinin immunostaining patterns in both ganglionic and aganglionic hd intestinal specimens and to compare them with control specimens. materials and methods ...
Abnormal distribution of sarcoglycan subcomplex in colonic smooth muscle cells of aganglionic bowel.
Hirschsprung's disease (HD) is a development disorder of the enteric nervous system in which the altered innervation explains the inability of the aganglionic segment to relax. Impairment of cytoskeleton in SMC of aganglionic bowel has been shown. Sarcoglycan subcomplex (SG) may support the development and maintenance of muscle cells. We examined the SG subunit expression in colonic aganglionic...
OBJECTIVES Definite diagnosis of Hirschsprung's disease (HD) is based on histopathological study, but there are limitations associated with standard histology and histochemistry in this regard. The aim of this study was to investigate calretinin immunostaining patterns in both ganglionic and aganglionic HD intestinal specimens and to compare them with control specimens. MATERIALS AND METHODS ...
Hirschsprung's disease is characterized by absence of ganglion cells in submucosal and myenteric plexus of distal bowel. Most cases become manifest during the neonatal period, but in rare instances, this disease is initially diagnosed in adult age. It usually presents as severe constipation with colonic dilatation proximal to the aganglionic segment. The treatment is surgical, removing the agan...
Hirschsprung disease (HSCR, aganglionic megacolon) is the main genetic cause of functional intestinal obstruction with an incidence of 1/5000 live births. This developmental disorder is a neurocristopathy and is characterised by the absence of the enteric ganglia along a variable length of the intestine. In the last decades, the development of surgical approaches has dramatically decreased mort...
In 1886, Harald Hirschsprung first described two cases of infantile constipation with colonic dilation, but he did not suggest any etiology or therapeutic option. Over the past 30 years, many studies have revealed the clinical presentation, radiological and histological diagnoses, surgical procedures, epidemiology, and associated genetics related to colonic dilation. Hirschsprung’s disease (HD)...
Hirschsprung disease (HSCR, aganglionic megacolon) represents the main genetic cause of functional intestinal obstruction with an incidence of 1/5000 live births. This developmental disorder is a neurocristopathy and is characterised by the absence of the enteric ganglia along a variable length of the intestine. In the last decades, the development of surgical approaches has importantly decreas...
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