نتایج جستجو برای: interferon type i
تعداد نتایج: 2250534 فیلتر نتایج به سال:
conclusions lrrfip1 and its mediated production of type i interferon play a role in controlling hcv infection. the findings of this study provide new target for hcv treatment and contribute to development of anti-hcv drugs. results lrrfip1 increased the expression of ifn-β in hepatocytes with or without hcv infection. induction of ifn-β by lrrfip1 was enhanced with the presence of hepatitis c v...
Scientists have been investigating the critical role type 1 interferons (IFN-I) play in controlling viral infections for more than 50 y. Common pathogen motifs present on viral particles trigger intracellular and membrane-associated pattern recognition receptors, leading to the production of IFN-I and rapid expression of interferon stimulated genes (ISIGs). ISIGs encode proteins with direct ant...
Innate immune responses against viral infection, especially the induction of type I interferon, are critical for limiting the replication of the virus. Although it has been shown that DNA can induce type I interferon, to date no natural DNA ligand of a virus that induces type I interferon has been described. Here we screened the genome of murine gammaherpesvirus 68 with mutations at various gen...
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