background: polycystic ovarian syndrome (pcos) is a common disease among women in fertility ages and cause severe insulin resistance. hyperhomocysteinaemia is said to be among the features of pcos that could influence its outcome. objective: this study aimed to investigate whether hyperhomocysteinaemia exists in pcos and if it is related to insulin resistance in the affected patients. materials...

objective: to determine the association between serum 25 - hydroxy vitamin d concentration and anthropometric indices in patients with polycystic ovarian syndrome (pcos). materials and methods: this is a descriptive cross - sectional study which was carried out on women with pcos aged 19-39 years old referred to an infertility clinic of alzahra hospital, rasht, iran during september2011- march2...

Insulin signaling plays a key role in glucose uptake, glycogen synthesis, and protein lipid synthesis. In insulin-resistant states like obesity type 2 diabetes mellitus, these processes are dysregulated. Regular physical exercise is potential therapeutic strategy against insulin resistance, as an acute bout of increases disposal during the activity for hours into recovery. Chronic activation pr...

Background: To compare thyroid volume , thyroid stimulating hormone (TSH) , Free T4  and  prevalence of thyroid nodules between obese and  non-obese subjects .Also,  association  between BMI  and insulin resistance status with various parameters of thyroid gland was evaluated. Methods: Fifty –two patients with obesity and 38 normal body mass index (BMI ) volunteers, aged 20-50 years , were enr...

Insulin resistance is a condition in which insulin signaling and action are impaired in insulin sensitive tissues and results in hyperglycemia, hyperlipidemia and type 2 diabetes mellitus. Our previous studies have shown that rosa damascena has antihyperglycemic effects on diabetic and normal rats. Therefore, we conducted a study to evaluate the effect of this medicinal plant on insulin sensiti...

abstract introduction: there is limited knowledge available on the metabolism of glucose in the brain, an insulin insensitive organ. insulin receptors hybridize with insulin like growth factor receptor (igf-i) to transduce the signals in different areas of the brain. in this article we aimed at investigating whether the expression of igf-i receptor and igf-i binding proteins (igfbp1) is changed...