lillie is known about the sexual differences in volume of human insular cortex in normal subjects and those suffering from ncurodcgcncrativc diseases. the objective of this study is 10 investigate the sex difference in volume of the left insular cortex in normal right-handed subjects versus subjects suffering from alzheimer and parkinson diseases. this study was performed on 72 normal human bra...

objective: this study was conducted to determine the changes in the insular cortex in alcohol dependent subjects, and to compare the same with controls, the associated clinical findings. methods: the study group consisted of 30 subjects with alcohol dependence syndrome (ads) selected randomly from the out patient services of the department of psychiatry of a tertiary care hospital. the control ...

Since the first report by Cechetto and Saper (1987) showing the viscerotopic sensory representation in the insular cortex, various studies on the posterior insular cortex have been performed. We previously studied the response properties of neurons in the rat insular cortex to gustatory, visceral and nociceptive stimulation, and to electrical stimulation of the various sensory nerves (chorda ty...

Insular cortex epilepsy is an under-recognized, localization-related syndrome. The presence of this condition could account for the surgery treatment failure seen in a portion of patients with temporal epilepsy, as well as a portion of those with frontal and parietal lobe epilepsy. Most cases of intractable temporal epilepsy are associated with insular cortex involvement. In this review, we wil...

BACKGROUND Various functional resonance imaging, magnetoencephalographic and lesion studies suggest the involvement of the insular cortex in the control of swallowing. However, the exact location of insular activation during swallowing and its functional significance remain unclear. CASE PRESENTATION Invasive electroencephalographic monitoring was performed in a 24-year-old man with medically...

Aims Insular cortex is a brain region critical for processing of the sensation. Purinergic receptors are involved in the formation of chronic pain. The aim of the present study was to explore the role and mechanism of P2X3 receptors (P2X3Rs) in insular cortex in chronic visceral pain. Methods Chronic visceral pain in adult rats was induced by neonatal maternal deprivation and measured by detect...

Empathy refers to the ability to perceive and share another person's affective state. Much neuroimaging evidence suggests that observing others' suffering and pain elicits activations of the anterior insular and the anterior cingulate cortices associated with subjective empathetic responses in the observer. However, these observations do not provide causal evidence for the respective roles of a...

The insular cortex is a multimodal brain region with regional cytoarchitectonic differences indicating various functional specializations. As a multisensory neural node, the insular cortex integrates perception, emotion, interoceptive awareness, cognition, and gustation. Regarding the latter, predominantly the anterior part of the insular cortex is regarded as the primary taste cortex. In this ...