background most patients with trauma experience different levels of pain. due to side effects as well as economic burden of drugs used for pain relief after trauma commonly, it is important to use low-cost methods independently or combined with drugs to alleviate pain. objectives therefore, this study aimed to investigate the effects of topical sesame oil on pain severity and frequency of recei...

cerebral vasospasm considered to be a serious cause of morbidity and mortality following subarachnoid haemorrhage (sah).despite several available therapeutic options, current protocols do not prevent major consequences of vasospasm. inflammation is believed to play an important role in post-haemorrhagic vasospasm. meloxicam is a non-steroidal anti-inflammatory drug. the aim of this study was to...

alzheimer's disease (ad) is a chronic neurodegenerative disease that accounts for 60 to 80 percent of all dementia cases. the exact cause of alzheimer`s disease is still unknown, but recent studies suggest neuro-inflammation as an important part of the pathogenesis of the disease. this brings in mind using non-steroidal anti-inflammatory drugs (nsaid) as treatment or prevention of the dise...

introduction: post-endodontic pain is one of the main problems for both patients and dentists. the purpose of this study was to compare the effectiveness of premedication with indomethacin and ibuprofen for management of postoperative endodontic pain. methods and materials: in this clinical trial, mandibular molars with irreversible pulpitis were endodontically treated in 66 patients. the medic...

background: peritendinous adhesions after repairing an injury to the digital flexor tendons are a major problem in hand surgery. non-steroidal anti-inflammatory drug therapy may affect tendon healing and the development of peritendinous adhesions. the aim of this study was to evaluate ibuprofen effect in patients function after flexor tendon surgical repair.   method: thirty-five patients, who ...

anti-inflammatory activity has been reported for a few of antidepressant drugs and in contrary sertraline has potentiated inflammation. in this study, anti-inflammatory effect of a collection of antidepressant drugs belonging to different classes was evaluated to help a rational selection of these drugs in disease conditions such as association of depression or anxiety with inflammatory disease...

background: although helicobacter pylori and non-steroidal anti-inflammatory drugs (nsaids) are the main causes of peptic ulcers disease (pud), recently the prevalence of idiopathic peptic ulcer (ipu) is increasing in most parts of the world. the aim of this study was to assess the prevalence of ipu in kerman, the center of largest province in south-east iran. methods : we included 215 patients...

tooth pulpal nerves include sympathetic and sensory nerves that originate from trigeminal ganglion .from the terminal of these sensory nerves neuropeptides are secreted that are neuromodulators and neurotransmitters. one of them is cgrp (calcitonin gene-related protein) which has a vasodilatory effect on pulpal vessels. near abscess and moderate injuries, this neuropeptide can lead to neural fi...