objective(s): electrical inhomogeneity between ischemic and non ischemic myocardium is the basis of arrhythmia which occurs following coronary artery occlusion. the leakage of potassium from the ischemic region to the non ischemic region is very effective in the generation of these arrhythmias. the aim of this study is to research the effect of atp-dependent potassium (katp) channel blocker (gl...

conclusions the primary treatment for gh-producing adenoma is surgery; however, this patient has high surgical risk from her severe cardiomyopathy. radiotherapy poses a greater risk because of increased cerebrovascular mortality. somatostatin receptor ligands are significantly associated with improvement of cardiovascular and hemodynamic parameters. dopamine agonists must be considered regardle...

myocardial infarction is a common presentation of coronary artery disease and the leading cause of death worldwide. the present study was investigated potential resistance to ischemia-reperfusion (i/r) injuries following administration of methanolic (meoh) extract of scrophularia frigida (s. frigida) in isolated rat heart. male wistar rat hearts (n= 8-10) were isolated and allowed to equilibrat...

silent brain infarcts (sbi) are associated with an increased risk of subsequent stroke. sbi are incidentally revealed by ct or mri executed in stroke patients. a prospective study was undertaken involving 200 consecutive patients aged >45 years with brain infarct admitted in university of alberta hospital, canada (100 patients) and valie-asr hospital, iran (100 patients) in 2003. patients were ...

Objective(s): Electrical inhomogeneity between ischemic and non ischemic myocardium is the basis of arrhythmia which occurs following coronary artery occlusion. The leakage of potassium from the ischemic region to the non ischemic region is very effective in the generation of these arrhythmias. The aim of this study is to research the effect of ATP-dependent potassium (KATP) channel blocker (gl...

this study intended to assess the efficacy of acute administration of natural honey on cardiac arrhythmias and infarct size when it is used during the normothermic ischemia in isolated rat heart. during 30 min of regional normothermic ischemia followed by 120 min of reperfusion, the isolated hearts were perfused by a modified drug free krebs-henseleit solution (control) or the solution containi...

recently a potent anti-inflammatory effect of hydroalcoholic extract of the aerial parts of the sterile stems of stachys inflata has been reported. this study examined whether hydroalcoholic extract isolated from aerial parts of non-flowering stems of stachys inflata (standardized to contain 4.5% caffeic acid derivatives) reduce myocardial infarct size arising from coronary artery occlusion (30...

objective: recent studies have shown that the use of prolonged and intermittent normobaric hyperoxia (95%) decrease the infarct volume of stroke. the aim of current study was to study the effect of an oxygen radicals-scavenger applied during intermittent normobaric hyperoxia on infarct volume in the rat brain and neurologic deficit. materials and methods: male wistar rats (250-350 g) were divi...

introduction: in the current study, protective effect of natural honey applied during ischemia/reperfusion (i/r) was studied on infarct size in ischemic heartheart. methods: ischemic hearthearts (n=8 per group) were mounted on a langendorff apparatus at constant pressure then subjected to 30 min regional ischemia followed by 120 min reperfusion. in control group, the hearts were perfused by a m...

introduction: it has been reported that traumas such as transverse abdominal incision before myocardial ischemia result in a significantly decreased infarct size. this phenomenon is named remote preconditioning of trauma. since small skin burn is one of most common traumas, the effect of this injury on ischemia-induced arrhythmias and infarct size was investigated in a rat model of ischemia-rep...