AIM To investigate whether extracutaneous infantile haemangioma-like tumours are immunohistochemically similar to cutaneous infantile haemangiomas. METHODS Mammary, salivary gland, liver (one each), and placental (two cases) capillary haemangiomas and typical examples of cutaneous (eight cases) infantile haemangioma were investigated immunohistochemically for alpha smooth muscle actin and Glu...

infantile haemangiomas (ih) are the most common vascular tumors occurring in early childhood, with a prevalence of approximately 5-10% of infants. these vascular tumors are divided into two main groups including infantile haemangioma and vascular malformations. although, haemangioma of infancy are common, benign and self-limited tumors, a significant percent of these lesions are associated with...

OBJECTIVE To examine the effects of bleomycin A5 on infantile maxillofacial haemangiomas. METHODS Bleomycin A5 was given by multiple intralesinoal injections and the dosage was given according to the age of the patient and size of the lesion. Parts of patients were accompanied by prednisone treatment (2-5 mg/kg, po, QOD. RESULTS All the haemangiomas involutes completely after treated with b...

Infantile haemangioma therapy has long been a wait-and-see policy. Since recent development of laser and light therapy, pulsed dye laser has been successfully used for treating superficial haemangiomas. Few studies have been published about treatment with intense pulsed light (IPL) to assess the risk/benefit of IPL in the treatment of infantile haemangiomas during their early proliferative phas...

Infantile haemangiomas are common benign tumours that do not require treatment unless they cause significant functional impairment or disfigurement. We report our experience with the off-label use of propranolol in 5 children with haemangiomas and review the relevant literature.

OBJECTIVE To assess the safety and efficacy of systemic propranolol for the treatment of complicated infantile haemangiomas. DESIGN Retrospective review of case notes of paediatric patients treated with propranolol for complicated infantile haemangiomas. SETTING Tertiary care children's hospital. PATIENTS All paediatric patients with complicated infantile haemangiomas who commenced treatm...

Cutaneous infantile haemangiomas affect approximately 1 in 10 children. They tend to follow a natural course of rapid proliferation during the first year of life and subsequently regress over 5-10 years. Most haemangiomas are non-problematic, but a few become problematic, through ocular, airway or functional impairment, or ulceration. Oral propranolol therapy has been observed to inhibit the pr...

Infantile haemangiomas are the most common benign tumour of infancy. However the majority are self-resolving and only a small minority of cases require treatment, with various different medications being used in the past. Over the last few years, propranolol, a non-selective β-blocker, has become a popular and successful treatment for infantile haemangiomas. However, further research on its saf...

Sir, Infantile haemangioma is a fairly common vascular tumour of the skin in infancy. In contrast, infantile subglottic haemangioma is rare, accounting for about 1.5% of all congenital laryngeal anomalies (1). However, it often causes stridor in infancy and sometimes leads to life-threatening respiratory distress (2). We report here a case of infantile haemangiomas on the face, neck and chest t...

Laryngeal haemangioma is commonly seen in children. Adult laryngeal haemangiomas are rare and usually involve the supraglottic region. Most common symptom includes dysphagia, dysphonia and shortness of breath. Detailed history, fiberoptic laryngoscopy and computerized scanning may suggest benign nature of the lesion but diagnosis is only confirmed by a biopsy. In comparison to infantile haemang...