background clindamycin is a frequently used antimicrobial therapeutic medicine used for the treatment of skin and soft tissue infections caused by staphylococcus aureus strains. resistance to this antibiotic is either constitutive or inducible. constitutive resistance to clindamycin could be detected by standard susceptibility testing methods. inducible clindamycin resistance could not be detec...

background: macrolides, lincosamides and type b streptogramins (mlsb) are commonly used for the treatment of staphylococcal infections. inducible mlsb resistance (imlsb) cannot be identified by standard methods of antibiotic susceptibility testing. d-test appears to be a reliable indicator of imlsb strains. the aim of this study was to determine the prevalence of clindamycin resistance phenotyp...

background and objectives: resistance to macrolide can be mediated by erm and msra genes in staphylococcus aureus . there are the evidences that show erm genes may be causative agent of inducible or constitutive resistance. the aim of this study was to investigate the incidence of inducible clindamycin resistance and determine the most frequency of erm and msr a genes among s. aureus isolates. ...

background and objectives: accurate designation of antimicrobial susceptibility pattern of the infecting microorganisms is an important crucial factor in making appropriate therapeutic decisions. macrolide, lincosamide and streptogramin b antibiotics are in a family, reserved as an alternative approach in treatment of resistant gram positive cocci. amongst them, clindamycin has been considered ...

background: clindamycin inducible resistant staphylococcus aureus (s.aureus) isolates can cause failure in treatment with this antibiotic. biofilm production via polysaccharide intercellular adhesion (pia) contributes in the colonization of s. aureus, resulting in the initiation of different diseases. the aim of this study was to detect icaadbc genes among isolates of s.aureus with inducible re...

background and objectives: macrolide, lincosamide and streptogramin b (mlsb) antimicrobial agents are widely used in the treatment of staphylococcal infection. clindamycin is the medicine of choice for some staphylococcal infections, particularly skin and soft tissues infections. erythromycin and clindamycin are two distinct classes of antimicrobial agents which inhibit protein synthesis in bac...

background and objective: the d-test is performed by placing clindamycin and erythromycin impregnated disks at a standard distance on the agar plate then looking for the flattening of inhibition zone around the clindamycin disk. a positive d-test indicates clindamycin inducible resistance and also predicts treatment failure possibility of this antibiotic in clinic. prevalence of staphylococcal ...