anterior cruciate ligament (acl) reconstruction surgery has significantly evolved in recent years. this has led to development of new technologies that facilitate the diagnosis of acl injury and the application of state of the art methods for treatment. in particular, individualized anatomical acl reconstruction aims to restore native acl function. treatment is tailored to each patient based on...

Anterior cruciate ligament (ACL) reconstruction surgery has significantly evolved in recent years. This has led to development of new technologies that facilitate the diagnosis of ACL injury and the application of state of the art methods for treatment. In particular, individualized anatomical ACL reconstruction aims to restore native ACL function. Treatment is tailored to each patient based on...

Doctors use statistics to advance medical knowledge; we use a medical analogy to introduce statistical inference “from scratch” and to highlight an improvement. Your doctor, perhaps implicitly, predicts the effectiveness of a treatment for you based on its performance in a clinical trial; the trial patients serve as controls for you. The same logic underpins statistical inference: to identify t...

Doctors use statistics to advance medical knowledge; we use a medical analogy to introduce statistical inference “from scratch” and to highlight an improvement. Your doctor, perhaps implicitly, predicts the effectiveness of a treatment for you based on its performance in a clinical trial; the trial patients serve as controls for you. The same logic underpins statistical inference: to identify t...

Abstract Estimation and evaluation of individualized treatment rules have been studied extensively, but real-world resource constraints received limited attention in existing methods. We investigate a setting which is intervened upon based on covariates to optimize the mean counterfactual outcome under cost when random. In particularly interesting special case, an instrumental variable correspo...

For the past few decades, scholars in statistical and social sciences have acknowledged that heterogeneity is prevalent subjects of their studies. The literature on individualized treatments...