Some epithelial cells display asymmetry along an axis orthogonal to the apical-basal axis, referred to as planar cell polarity (PCP). A Frizzled-mediated feedback loop coordinates PCP between neighboring cells, and the cadherin Fat transduces a global directional cue that orients PCP with respect to the tissue axes. The feedback loop can propagate polarity across clones of cells that lack the g...

AIM Propofol is a widely used anesthesia induction agent and is easily accessible in most healthcare facilities. Unlike regulated or schedule drugs, propofol is inconsistently tracked, leading to inaccurate inventories, incorrect billing, and unrecognized diversion. The goal of this project was to implement a new method of tracking propofol in a single setting, with the aim of accounting for 10...

The causality properties of space-time models with traversable wormholes are considered. It is shown that relativity principle cannot be applied to the motion of the wormhole’s mouths in the outer space and the dynamical wormhole transformation into the time machine is impossible. The examples of both causal and noncausal spacetime models with traversable wormholes are also considered. Some pro...

(Developmental Cell 16, 83–92; January 20, 2009) In following up the experiments reported in this paper, we have discovered that the polarity phenotypes ofDystroglycan and perlecan mutant clones under starvation conditions shown in Figures 4, 5, 6F, 6H, and 6J are the result of an artifact. We now believe that these panels do not represent real clones with a polarity phenotype, but rather false...

Page 1 of 1 (page number not for citation purposes) In a recent study on nurses’ ability to predict volume status after subarachnoid haemorrhage, we found very low predictive values [1]. In a letter to the editor, Dane [2] argued that an error in statistics ‘makes any reasonable conclusions impossible’. Because Dr Dane was the statistical reviewer of our manuscript, both the authors and the edi...