References 1. Inspections, compliance, enforcement, and criminal investigations: Novartis International AG 11/18/11 [warning letter]. Silver Spring (MD): Food and Drug Administration (US); 2011 Nov 18 [cited 2012 Sep 20]. Available from: www.fda.gov/ICECI/EnforcementActions/WarningLetters/ucm281843.htm 2. Lettre aux clients (15-16 février). Boucherville (QC): Sandoz Canada Inc.; 2012 Feb 15 [ci...

We develop an approach to utilize anisotropic metamaterials to solve one of the fundamental problems of modern plasmonics--parasitic scattering of surface waves into free-space modes, opening the road to truly two-dimensional plasmonic optics. We illustrate the developed formalism on the examples of plasmonic refractor and plasmonic crystal, and discuss limitations of the developed technique an...

Flow cytometry (FCM) is a fluorescence-based single-cell experimental technology that is routinely applied in biomedical research for identifying cellular biomarkers of normal physiological responses and abnormal disease states. While many computational methods have been developed that focus on identifying cell populations in individual FCM samples, very few have addressed how the identified ce...

An assay technique, homogeneous enzyme immunoassay, is described for the quantitative determination of morphine derivatives in biological fluids. An enzyme is labeled with morphine. When the enzymelabeled morphine is bound by antimorphine antibodies, the enzyme is rendered inactive. Free morphine competes with enzyme-morphine for antibody binding sites preventing inhibition of enzyme activity. ...

in this study, we assess the impact of oil price changes on the macroeconomic variables of some oil importers in oecd countries, including usa, italian, france and japan during the period 1960-2002. the results for different countries imply asymmetric impact of oil price changes on gdp growth rates; moreover, the results show that monetary shocks are an important and noticeable factor explainin...

Evaluations of speech intelligibility based on a read passage are often used in the clinical situation to assess the impact of the disease and/or treatment on spoken communication. Although scale-based measures are often used in the clinical setting, these measures are susceptible to listener response bias. Automatic evaluation tools are being developed in response to some of the drawbacks of p...

In France, human botulism is mainly food-borne intoxication, whereas infant botulism is rare. A total of 99 group I and II Clostridium botulinum strains including 59 type A (12 historical isolates [1947-1961], 43 from France [1986-2013], 3 from other countries, and 1 collection strain), 31 type B (3 historical, 23 recent isolates, 4 from other countries, and 1 collection strain), and 9 type E (...