Objective- To evaluate antinociceptive efficacy of pre- versus post-incisional morphine, tramadol and meloxicam using tail-flick test in an incisional model of pain in rats. Design- Prospective, randomized experimental study. Animals- Eighty, adult, male Wistar rats weighing 250–300 g. Procedures- Animals were randomly divided into eight groups to receive pre- or post-incisional (tail skin i...

BACKGROUND Annually approximately 100.000 patients undergo a laparotomy in the Netherlands. About 15,000 of these patients will develop an incisional hernia. Both open and laparoscopic surgical repair have been proven to be safe. However, the most effective treatment of incisional hernias remains unclear. This study, the 'INCH-trial', comparing cost-effectiveness of open and laparoscopic incisi...

BACKGROUND Incisional hernias occur at surgical abdominal incision sites, but the association with caesarean section (CS) has not been examined. AIM To determine whether CS is a risk factor for incisional hernia repair. MATERIALS AND METHODS Population-based cohort study in Australia using linked birth and hospital data for women who gave birth from 2000 to 2011. Survival analysis was used ...

BACKGROUND The purpose of this study was to clarify the incidence and risk factors for incisional surgical site infections (SSI) in patients undergoing elective open surgery for colorectal cancer. METHODS We conducted prospective surveillance of incisional SSI after elective colorectal resections performed by a single surgeon for a 1-year period. Variables associated with infection, as identi...

Incisional hernia is a common postoperative complication following open abdominal surgery with incidence varying between 3% and 20%. Approximately half of all incisional hernias are diagnosed within 1 year following surgery. In the United Kingdom alone, about 10,000 incisional hernia repairs are performed annually. Incisional hernia repairs are generally elective with emergency repair due to in...

BACKGROUND The treatment of incisional hernia (IH) is a current problem in modern surgery. Many important aspects of incisional hernia surgery are yet to be answered, especially the choice of surgical technique and its adaptation to the individual patient. The aim of this experts' meeting was to resolve some current questions in incisional hernia surgery and to organise an international hernia ...

Postoperative pain is the main obstacle for safely rapid recovery of patients undergoing laparoscopic cholecystectomy (LC). In this study, we systemically evaluated the analgesic efficacy of intraperitoneal and incisional ropivacaine injected at the end of the LC. A total of 160 patients, scheduled for elective LC, were allocated into four groups. Group Sham received intraperitoneal and incisio...

Background: Incisional hernia is a hernia that protrudes through a defect in a previous abdominal wound, and is one of the complications after abdominal surgery. Many risk factors seem to be associated with its development, and there are different treatment modalities from conservative management to operative repair whether open or laparoscopic. Objective: To assess the relation between the typ...

Roux-en-y gastric bypass (RYGB) has become the most common operation in the United States for morbid obesity. Even in the laparoscopic era many procedures are still done via laparotomy. Incisional hernias are a complication of any abdominal surgery with obese patients being at increased risk. Patients undergoing open RYGB over 6 years were reviewed to evaluate the risk factors for the developme...

previous studies have suggested that ketamine, an n-methyl-d-aspartate (nmda) receptor antagonist, provides a pre-emptive analgesic effect and pre-emptive analgesia improves postoperative pain management. the aim of this study was to determine the effict of pre-incisional vs. post-incisional intravenous low dose of racemic ketamine in postoperative pain in children undergoing inguinal hernia re...