نتایج جستجو برای: in situ forming sol gel

تعداد نتایج: 17010565  

Journal: :iranian journal of pharmaceutical sciences 0
golnar dorraj department of pharmaceutics and nanotechnology, school of pharmacy, shahid beheshti university of medical sciences, po box: 14155-6153, tehran, iran. hamid r. moghimi department of pharmaceutics and nanotechnology, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran. pharmaceutical sciences research center, shahid beheshti university of medical sciences, tehran, iran.

preparation and characterization of thermoresponsive in-situ forming poloxamer hydrogel for controlled release of nile red-loaded solid lipid nanoparticles. nanoparticles (nps) are cleared rapidly from systemic circulation and do not provide sustained action in most cases. to solve this problem, this investigation introduces an erodible in-situ forming gel system as potential vehicles for prolo...

Golnar Dorraj, Hamid R. Moghimi

Preparation and characterization of thermoresponsive in-situ forming poloxamer hydrogel for controlled release of Nile red-loaded solid lipid nanoparticles. Nanoparticles (NPs) are cleared rapidly from systemic circulation and do not provide sustained action in most cases. To solve this problem, this investigation introduces an erodible in-situ forming gel system as potential vehicles for prolo...

Journal: :iranian journal of pharmaceutical research 0
golnar dorraj department of pharmaceutics and nanotechnology, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran. hamid reza moghimi department of pharmaceutics and nanotechnology, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran.

abstractvarious nanoparticles have been investigated as novel drug delivery systems, including solid lipid nanoparticles (slns). due to their rapid clearance from systemic circulation, nanoparticles do not provide sustained action in most cases. different strategies have been employed to overcome this problem. in this direction, the present study introduces erodible in-situ forming gel systems ...

AbstractVarious nanoparticles have been investigated as novel drug delivery systems, including solid lipid nanoparticles (SLNs). Due to their rapid clearance from systemic circulation, nanoparticles do not provide sustained action in most cases. Different strategies have been employed to overcome this problem. In this direction, the present study introduces erodible in-situ forming gel systems ...

AbstractVarious nanoparticles have been investigated as novel drug delivery systems, including solid lipid nanoparticles (SLNs). Due to their rapid clearance from systemic circulation, nanoparticles do not provide sustained action in most cases. Different strategies have been employed to overcome this problem. In this direction, the present study introduces erodible in-situ forming gel systems ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه فردوسی مشهد - دانشکده علوم پایه 1391

food safety is considered as an important world concern. the detection of pathogen and toxic materials in food has an important role in public health care. in recent years, the applications of microbial biosensor have been developed as a new approach for toxicity control. luminescent microbial biosensor is an appropriate biological tool for protection of natural environment. this type of biosen...

2017
Zugong Yu Fanxi Guo Yangyang Guo Zhenrui Zhang Feng Wu Xiaoqing Luo

The objective of this study was to develop an injectable in situ forming gel system based on Poloxamer for sustained release of Astragalus polysaccharide (APS), thus achieved once or twice administration instead of frequent dosing during long-term treatment. The optimal formulation is 10 g APS, 18 g poloxamer 407, 2 g poloxamer 188, 0.15 g CMC-Na, 0.85 g sodium chloride in 100 ml gel in situ wh...

Journal: :European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2013
Laleh Erfani Jabarian Mohammad Reza Rouini Fatemeh Atyabi Alireza Foroumadi Seyed Mahdi Nassiri Rassoul Dinarvand

The objective of this study was to develop a controlled delivery system for PEGylated octreotide using a Poloxamer based in situ gel forming polymer. PEGylated octreotide kept its full biological activity and higher serum half-life compared to the original octreotide. The designed drug delivery system contained low concentration of Poloxamer 407 (P407) (<0.16%) with polyvinyl alcohol (PVA) as a...

2015
Golnar Dorraj Hamid Reza Moghimi

Various nanoparticles have been investigated as novel drug delivery systems, including solid lipid nanoparticles (SLNs). Due to their rapid clearance from systemic circulation, nanoparticles do not provide sustained action in most cases. Different strategies have been employed to overcome this problem. In this direction, the present study introduces erodible in-situ forming gel systems as poten...

2013
Jaya Raja Kumar Selvadurai Muralidharan Sokkalingam Arumugam Dhanaraj

Smart polymeric systems represent promising means of delivering the drugs; these polymers undergo sol-gel transition, once administered. In-situ gel structure occurs due to one or combination of different stimuli like pH change, temperature modulation and ionic exchange. The formation of gels depends on factors like temperature modulation, pH change, presence of ions and ultra violet irradiatio...

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