Maternal consumption of folic acid before pregnancy and during early pregnancy is associated with a reduced risk for some birth defects. Whether folic acid can reduce the risk for imperforate anus is unknown. As part of a public health campaign conducted in China from 1993 through 1995, the outcomes of pregnancies of > or =20 weeks' gestation were evaluated among women using folic acid suppleme...

Cornelia de Lange syndrome is a dominantly inherited, genetically heterogeneous and clinically variable syndrome with multiple congenital anomalies and developmental delay. Gastrointestinal anomalies are common and an important cause of morbidity and mortality. We report on a newborn with a molecularly confirmed Cornelia de Lange syndrome who had an imperforate anus. This is the third report of...

Aim: The overall aim of this thesis was to explore psychosocial consequences on children with high and intermediate imperforate anus and their parents. Material/Methods: Paper I was an explorative study involving interviews. The purpose was to illuminate the children’s and parents’ experiences of imperforate anus (IA) and to create a baseline for further research. In Papers II-V, study-specific...

the standard approach to management of high imperforate anus is colostomy in the newborn period followed by posterior saggital anorectoplasty (psarp) at 6 to 12 months of age. the purpose of this study was to determine whether a one-stage repair by primary psarp in the newborn period could be performed without clear determent to the patient’s functional result. totally 30 newborns with high imp...

Bombay Medical Service. I have read with interest the case of " imperforate anus" of a child four months old, published in the current issue of your journal by Surgeon-Major Ma the w, Civil Surgeon of Mozufferpore. It would seem that it is one of congenital malformation, that " this child is in capital condition, lively, and, as far as can be judged, in the enjoyment of perfect healththat " the...

The Pallister-Hall syndrome is characterised by specific facial anomalies, postaxial polydactyly, imperforate anus, and brain anomalies including a diencephalic hamartoblastoma. The hallmarks of the McKusick-Kaufmann syndrome are hydrocolpos owing to vaginal atresia, postaxial polydactyly, imperforate anus, and congenital heart defects. We report a patient with the unique features of hydrocolpo...