background: immunoradiometric assay is one of the most common and precise methods for determination of prostate specific antigen (psa) in clinical laboratories. usual use of human serum in routine assays has many disadvantages such as easy contamination and precipitation, instability and unavailability. thus in order to avoid these problems the artificial matrix was used which acts similar to h...

Do Commercially Available Assay Kits for B-Type Natriuretic Peptide Measure Pro-BNP1-108, as Well as BNP1-32? To the Editor: We read with great interest the recent article by Heublein et al1 on plasma pro-BNP1-108 measurement with commercially available assay kits and the effect of pro-BNP1-108 on cGMP levels. They demonstrated that Shionogi’s or Biosite’s triage assay kit did not cross-react w...

We evaluated four commercial kits for measuring serum ferritin, based on three techniques: immunoradiometric assay, radioimmunoassay, and enzyme immunoassay. The kits evaluated were those manufactured by Abbott Laboratories, Clinical Assays, Corning Medical, and Ramco. Two of the immunoradiometric kits showed satisfactory results with respect to sensitivity and precision; they should be useful ...

To verify this assumption we evaluated another kit, the “/3hCG MAIA-clone immunoradiometric assay” (Serono), comparing the effects of lipemia on the results obtained with it and with Clinical Assays’ monoclonal antibody kits; we used sera from seven male patients, selected for hipemia. We also examined the effects of free fatty acids at concentrations of 1 g/L in hCG-free serum. Both assays wer...

We evaluated three commercially available immunoradiometric assays for serum ferritin, with particular emphasis on the statistical validity of the results. The data show that it was unusual (a) for dose/response relationships of the standards to be linear over the whole concentration range suggested by the manufacturers and (b) for dose/response relationships of test sera to parallel those of t...

introduction: prostate specific antigen (psa) is one of the most sensitive markers for diagnosis of prostate cancer. immunoradiometric kit (irma) is a common and sensitive method for determination of psa in clinical laboratories. this kit has four major components: solid phase coated with monocolonal antibody, pair antibody labelled with i-125, series of standards in different ranges of concent...