نتایج جستجو برای: imerslund

تعداد نتایج: 58  

Journal: :Blood 1999
D Xu R Kozyraki T C Newman J C Fyfe

Cubilin is a high molecular weight multiligand receptor that mediates intestinal absorption of intrinsic factor-cobalamin and selective protein reabsorption in renal tubules. The genetic basis of selective intestinal cobalamin malabsorption with proteinuria was investigated in a canine model closely resembling human Imerslund-Gräsbeck syndrome caused by cubilin mutations. Canine CUBN cDNA was c...

2017
Aziz Eghbali Mohammad Taghi Arzanian Fatemeh Malek Bibi Shahin Shamsian

Introduction Megaloblasc anemia is an uncommon problem in childhood most frequently associated with vitamin deficiency or gastrointesnal disease. The common causes of megaloblasc anemia are vitamin B12 (cobalamin) deficiency and folic acid deficiency. Familial selecve malabsorpon of vitamin B12 associated with proteinuria firstly was described by Imerslund (1960) and Grasbeck et al (1960) ...

Journal: :International Journal of Biomedical Research 2012

Journal: :Archives of disease in childhood 1966
S B Dimson

The extreme rarity of pernicious anaemia in childhood has been stressed by Lambert, Prankerd, and Smellie (1961) who, by insisting on positive evidence of intrinsic factor deficiency for the diagnosis, could accept unequivocally only 7 cases in the literature but added 2 of their own, who were sibs. They may have overlooked the case described by Wilkins (1957) which was later confirmed by McInt...

Journal: :Journal of Nepal Paediatric Society 2011

Journal: :Indian pediatrics 2009
S Madhavan M Vijayakumar Sarala Rajajee B R Nammalwar

A 14 year male adolescent born of 2nd degree consanguineous marriage presented with asymptomatic proteinuria and severe anemia. He had leucopenia, anisopoikilocytosis, megaloblastic erythropoiesis, megakaryocytes with low serum B12 level. His younger sibling was similarly affected. This combination suggested Imerslund-Grasbeck syndrome. The hemoglobin levels improved with injection of vitamin B...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید