Journal:
:international journal of hematology-oncology and stem cell research
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ehsan mohajeri department of pharmaceutics, faculty of pharmacy, kerman university of medical sciences, kerman, iran
behjat kalantari-khandani department of oncology and hematology, faculty of medicine, kerman university of medical sciences, kerman, iran
abbas pardakhty pharmaceutics research center, kerman university of medical sciences, kerman, iran
moeinadin safavi department of pathology, afzalipour medical faculty, kerman university of medical sciences, kerman, iran
mehdi ansari department of pharmaceutics, faculty of pharmacy, kerman university of medical sciences, kerman, iran
background: imatinib is known as the drug of choice for treatment of chronic myeloid leukemia (cml). for adults the recommended daily dosage of 400 mg requires simultaneous intake of up to four capsules or tablets each 100 mg. a new 400 mg film coated tablet developed due to the need to swallow multiple capsules or tablets per dose and that was a negative impact on treatment adherence. subjects...
