نتایج جستجو برای: il 6 pge2

تعداد نتایج: 1053944  

Dian Ratih Laksmitawati Maesaroh Maesaroh, Moordiani Moordiani, Ni Made Dwi Sandhiutami Nurul Fauziah, Wahyu Widowati,

Objective(s): Inflammation is an immune response toward injuries. Although inflammation is healing response, but in some condition it will lead to chronic disease such as rheumatoid arthritis, inflammatory bowel disease, atherosclerosis, Alzheimer’s and various cancer. Indonesian cassia (Cinnamomum burmanni C. Nees & T. Ness) known to contain coumarin, is widely used for alternative medicine es...

Journal: :iranian journal of basic medical sciences 0
ni made dwi sandhiutami faculty of pharmacy, university of pancasila, jl. srenseng sawah, jagakarsa, jakarta 12640, indonesia moordiani moordiani faculty of pharmacy, university of pancasila, jl. srenseng sawah, jagakarsa, jakarta 12640, indonesia dian ratih laksmitawati faculty of pharmacy, university of pancasila, jl. srenseng sawah, jagakarsa, jakarta 12640, indonesia nurul fauziah bimolecular and biomedical research center, aretha medika utama,jl. babakan jeruk 2 no 9, bandung 40163, indonesia maesaroh maesaroh bimolecular and biomedical research center, aretha medika utama,jl. babakan jeruk 2 no 9, bandung 40163, indonesia wahyu widowati medical research center faculty of medicine, maranatha christian university, jl. prof. drg. suria sumantri no 65 bandung 40164, indonesia

objective(s): inflammation is an immune response toward injuries. although inflammation is healing response, but in some condition it will lead to chronic disease such as rheumatoid arthritis, inflammatory bowel disease, atherosclerosis, alzheimer’s and various cancer. indonesian cassia (cinnamomum burmanni c. nees & t. ness) known to contain coumarin, is widely used for alternative medicine es...

Journal: :The Biochemical journal 2003
Kumudika I de Silva Asif N Daud JiangPing Deng Stephen B Jones Richard L Gamelli Ravi Shankar

Interleukin-6 (IL-6), a potent myeloid mitogen, and the immunosuppressive prostanoid prostaglandin E2 (PGE2) are elevated following thermal injury and sepsis. We have previously demonstrated that bone marrow myeloid commitment shifts toward monocytopoiesis and away from granulocytopoiesis during thermal injury and sepsis and that PGE2 plays a central role in this alteration. Here we investigate...

2014
Jung-Sun Cho In-Hye Han Hye Rim Lee Heung-Man Lee

PURPOSE Interleukin 6 (IL-6) and IL-8 participate in the pathogenesis of chronic rhinosinusitis with nasal polyps, and their levels are increased by prostaglandin E2 (PGE2) in different cell types. The purposes of this study were to determine whether PGE2 has any effect on the increase in the levels of IL-6 and IL-8 in nasal polyp-derived fibroblasts (NPDFs) and subsequently investigate the pos...

Journal: :Endocrine-related cancer 1999
A Singh A Purohit M W Ghilchik M J Reed

Prostaglandin E2 (PGE2) and cytokines, such as interleukin-6 (IL-6) or tumour necrosis factor a (TNFalpha) can regulate aromatase activity. In the present study we have compared their abilities to stimulate aromatase activity in fibroblasts derived from 'normal' breast adipose tissue proximal to a tumour or breast tumours. PGE2, TNFalpha and IL-6 plus its soluble receptor (IL-6sR) all increased...

Journal: :The Journal of Experimental Medicine 1994
G Strassmann V Patil-Koota F Finkelman M Fong T Kambayashi

Among other effects, prostaglandins (PG) of the E series are known to inhibit several acute and chronic inflammatory conditions in vivo and proinflammatory cytokine production by activated macrophages in culture. The research presented here demonstrates that the inhibitory effect of PGE2 on tumor necrosis factor alpha (TNF-alpha) and interleukin 6 (IL-6) production by lipopolysaccharide (LPS)-s...

Journal: :The Journal of pharmacology and experimental therapeutics 1998
L Zeng S An E J Goetzl

Human leukemic early T cells of the HSB.2 line coexpress the EP2, EP3 and EP4 subtypes of prostaglandin E2 (PGE2) receptors (Rs). EP3 Rs have previously been demonstrated to transduce PGE2 stimulation of secretion of matrix metalloproteinase (MMP)-9 by HSB.2 T cells through Ca++-dependent enhancement of MMP-9 mRNA transcription. We now show that PGE2 and the EP4/EP2/EP3 R-selective agonist miso...

1994
Fred Finkelman Miranda Fong Taku Kambayashi

Among other effects, prostaglandins (PG) of the E series are known to inhibit several acute and chronic inflammatory conditions in vivo and proinflammatory cytokine production by activated macrophages in culture. The research presented here demonstrates that the inhibitory effect of PGE2 on tumor necrosis factor oe (TNF-oL) and interleukin 6 (IL-6) production by lipopolysaccharide (LPS)-stimula...

2016
Nuntana Aroonrerk Nattisa Niyomtham Boon-ek Yingyoungnarongkul

OBJECTIVE To evaluate the effect of N-benzyl-4-bromobenzamide (NBBA) on lipopolysaccharide (LPS)-induced IL-6 and prostaglandin E2 (PGE2) production in human gingival fibroblasts (HGFs). MATERIAL AND METHODS The benzamide compound was synthesized. The condition for IL-6 production of HGFs after induction with LPS was optimized. The HGFs were incubated with NBBA (10 µg/ml) for 30 min before LP...

Journal: :Journal of leukocyte biology 2005
Yoshimi Shibata Akihito Nishiyama Hiroyoshi Ohata Jon Gabbard Quentin N Myrvik Ruth Ann Henriksen

Different populations of mononuclear phagocytes (MO) show considerable diversity of cellular function including prostaglandin E2 (PGE2) biosynthesis. Certain bacterial components enhance PGE2 biosynthesis differentially in selected populations of MO. Interleukin (IL)-10 is proposed to inhibit modulation of PGE2 biosynthesis by down-regulating prostaglandin G/H synthase-2 (PGHS-2) expression. To...

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