Background: As a chronic inflammatory condition, psoriasis results from an interaction between genetic and immunologic factors in a predisposing environment. In spite of compelling evidence for the role of T cells and cytokines in psoriasis, interleukin (IL)- 10 and IL-22 have not been sufficiently investigated. Objective: To assess the serum levels of IL-10 and IL-22 in patients with psori...

“T I drew, using a mirror; it is my own likeness, in the year 1484, when I was still a child,” wrote Albrecht Dürer about his first self-portrait, sketched with great confidence and skill when he was 13 years old (1). Fascinated by his own image, he continued to paint it throughout his life. His faithful dog once barked and wagged its tail at a newly completed self-portrait of his master, relat...

background & objective: interleukin (il)-10 is an important anti-inflammatory and immunomodulatory cytokine. some authors believe that single nucleotide polymorphisms (snp) in the promoter region of the il-10 gene have been associated with susceptibility to hiv infection and progression to aids, but its role is not clearly defined yet. the present study was undertaken to evaluate the associ...

the underlying mechanisms leading to the development of human t-cell lymphotropic virus type i (htlv-i) associated myelopathy/tropical spastic paraparesis (ham/tsp) in htlv-i infected individuals are not fully understood. host genetic factors appear to be involved as risk factors for developing ham/tsp. we investigated the possible contribution of interleukin-10 (il-10) as a risk factor to ham/...

background: cesarean section delivery can lead to much maternal morbidity. different cytokines have been reported to be influenced by the mode of delivery. objective: to investigate the influence of mode of delivery on maternal, placental and cord sera of interferon gamma (ifn-γ), interleukin-4 (il-4) and interleukin-10 (il-10) levels. methods: these three cytokines were measured using elisa in...

h. pylori  is a human pathogen that colonizes the epithelium of the stomach. the host immune response may influence the disease process, where cytokines play important roles in the development of disease. in this study, the concentrations of selected cytokines in the gastric antrum and stomach body mucosa and also in the serum were evaluated. eighty patients according to their rapid urease test...