BACKGROUND Current treatment of malignant melanoma of the leg includes ilioinguinal lymphadenectomy (IIL). Standard open IIL (open IIL) includes sectioning of the inguinal ligament to gain access to the iliac nodes. Extraperitoneal laparoscopic IIL (lap IIL) is a feasible, less aggressive approach. It can be combined with standard superficial lymphadenectomy for treatment of malignant melanoma....

S. R. J. Brueck University of New Mexico Department of Electrical and Computer Engineering Department of Physics and Astronomy Albuquerque, New Mexico 87131 and Center for High Technology Materials University of New Mexico Albuquerque, New Mexico 87106 E-mail: [email protected] Abstract. Imaging interferometric lithography (IIL) employs the resolution enhancement technique (RET) of off-axis i...

BACKGROUND Pseudomonas aeruginosa adhesion to animal/human cells for infection establishment involves adhesive proteins, including its galactose- and fucose-binding lectins PA-IL (LecA) and PA-IIL (LecB). The lectin binding to the target-cell receptors may be blocked by compatible glycans that compete with those of the receptors, functioning as anti-adhesion glycodecoys. The anti-adhesion treat...

PURPOSE To quantitate the level of difficulty and determine consistency of hemodynamic responses with various expiratory strain (ES) durations. METHODS Thirty-four healthy subjects performed the Valsalva maneuver (VM) with an ES duration of 10, 12, and 15 seconds in random order. Level of difficulty after each trial was rated 1 to 10, with 10 being the most difficult. Blood pressure and heart...

BACKGROUND Imidazolium ionic liquids (IILs) underpin promising technologies that generate fermentable sugars from lignocellulose for future biorefineries. However, residual IILs are toxic to fermentative microbes such as Saccharomyces cerevisiae, making IIL-tolerance a key property for strain engineering. To enable rational engineering, we used chemical genomic profiling to understand the effec...

Although it has been known for many years that T. spiralis muscle larvae (ML) can not invade intestinal epithelial cells unless they are exposed to the intestinal milieu and activated into intestinal infective larvae (IIL), which genes in IIL are involved in the process of invasion is still unknown. In this study, suppression subtractive hybridization (SSH) was performed to identify differentia...

In this paper, we study the factorability of linear time-varying (LTV) lossless filters and filter banks. We give a complete characterization of all degree-one lossless LTV systems and show that all degree-one lossless systems can be decomposed into a time-dependent unitary matrix followed by a lossless dyadicbased LTV system. The lossless dyadic-based system has several properties that make it...

Adoptive therapy with engineered T cells shows promising results in treating patients with malignant disease, but is challenged by incomplete responses and tumor recurrences. Here, we aimed to direct the tumor microenvironment in favor of a successful immune response by local secretion of interleukin (IL-) 12 and IL-18 by sadministered T cells. To this end, we engineered T cells with a melanoma...