background: pemphigus is an autoimmune bullous disease and it is unclear what triggers and deteriorates it. the current study aimed to evaluate whether increasing the igg antibody titer represents a good indicator of the pemphigus recurrence. objectives: the current study aimed to evaluate whether increasing igg titer is an indicator of the expected recurrence. patients and methods: the current...

Antiphospholipid antibodies (APLA) may be detected in normal pregnancies and also may cause thrombosis, recurrent fetal loss, placental infarction and preeclampsia. In the present study the possible differences in APLA titer between healthy pregnant women and preeclampsia cases without history of thrombosis was examined. The APLA titer in 50 healthy pregnant women with 50 preeclampsia cases wit...

OBJECTIVE To correlate the clinical course of the disease with the titer, the isotype profile and the switch of the anti-Ro/SSA antibodies in a cohort of patients affected by UCTD. METHODS One hundred selected patients with anti-Ro/SSA antibodies detected by counterimmunoelectrophoresis (CIE), and affected by UCTD with a mean follow-up of 7.6 years (SD 4.8 yrs.), were studied. The titer of Ig...

OBJECTIVE To study the humoral immune response directed at myelin oligodendrocyte glycoprotein (MOG)in pediatric patients with isolated and recurrent optic neuritis(ON). DESIGN Observational prospective case series. SETTING Six pediatric hospitals in Germany and Austria. PATIENTS Thirty-seven patients 18 years or younger with single or recurrent episodes of ON were recruited from 6 differ...

BACKGROUND The anti-Trypanosoma cruzi antibodies isotype profile in Chagas' disease has been studied in relation to different clinical manifestations. A high titer of IgG anti-T. cruzi antibodies is found in patients with cardiac involvement, while a high titer of IgA anti-T. cruzi antibodies is associated with digestive forms. OBJECTIVE The aim of this work was to analyze the IgG subclass re...

Antibodies are a class of biomolecules that has an important role in the immune system and lots of applications in biotechnological methods and in pharmaceutics. Production and purification of antibodies in laboratory animals is one of the first ways to manufacture of these prominent tools. The obtained antibodies from these process could be used in various types of bioassay techniques such as ...

it has been also reported that that h. pylori infection may be responsible for some endocrine disorders, such as autoimmune thyroid diseases, diabetes mellitus and primary hyperparathyroidism. h. pylori which express cytotoxin-associated gene a (caga) may be more virulent than those that do not. the aim was to evaluate the seroprevalence of anti-h. pylori igg and anti-caga  antibodies in patien...

Abstract This study aims to determine the most frequent titers of anti-A and anti-B (both presumed immunoglobulin [Ig]M IgG) in Iranian group O blood donors compare these titer values with those found other studies. In addition, alloantibody production plasma levels four IgG subclasses were compared between high-titer non–high-titer groups. investigated 358 samples. Based on results, two groups...

We determined the serum concentrations of IgA and IgG antibodies specific for Chlamydia trachomatis (C. trachomatis) by an indirect immunoperoxidase assay (IPAzyme kit, Savyon Diagnostics, Ltd., Bee, Shova, Israel) to evaluate their diagnostic significance in latent infections in males. Forty-five asymptomatic males whose wife or partner was suspected to be infected with C. trachomatis were stu...