background: malassezia are dimorphic, lipid-dependent yeasts, which are responsible for causing several cutaneous and sys­temic conditions. although cyclophilins (cyps) are highly conserved cytosolic proteins that catalyze the peptidyl-prolyl cis-trans isomerazation reaction before protein folding process, it has been suggestive of an allergen in a few numbers of fungi such as aspergillus fumig...

air pollutants are reported to increase the specific ige response to allergens. to study allergen proteins and determine the effect of air pollutants on the allergenic potential of pollen extracts, the extracts were injected intraperitoneally and subcutaneously in guinea pigs. the results were analyzed by skin prick test (spt), elisa and sds-page followed by immunoblotting. the pollen extract o...

the aim of this study was to evaluate the sensitivity of the population of fez and casablanca in morocco to dry white beans (phaseolus vulgaris) and to investigate the effect of food processing (heat and/or enzymatic hydrolysis by pepsin) on this sensitivity. work was based on a bank consisting of 146 sera from patients with atopic hypersensitivity in order to evaluate specific immunoglobulin e...

Background: Allergens are mostly composed of glycoprotein structures. It is believed that glycan-specific antibodies may lead to false-positive reactions in immunoassays. In this study we investigated the glycosylation state of grape allergens as well as the presence of antibodies to cross-reactive carbohydrate determinants (anti-CCDs) in sera from grape-sensitive individuals. Methods: Grape...

snail is one of the worst causes of food allergy. thus, the aim of this study was to identify the major and minor allergens of the local marine snail ( cerithidea obtusa ) and subsequently to investigate the impacts of heat treatment on the ige-binding activity of snail allergens. proteins from raw and heat-treated snails (boiled, roasted and fried) were extracted and then resolved by sodium do...

air pollutants are reported to increase the specific ige response to allergens. clinical tests and immonoblotting were performed with pollen grains of spartium junceum. to identify allergens and to determine the effect of air pollutants on the allergenicity of the pollen extracts, the pollen extracts were injected intraperitoneally and intracutaneously to guinea pigs. injection of the pollen ex...

allergy to prosopis juliflora (mesquite) pollen is one of the common causes of respiratory allergy in tropical countries. mesquite is widely used as street trees in towns and ornamental shade trees in parks and gardens throughout arid and semiarid regions of iran. the inhalation of mesquite pollen and several species of amaranthus/chenopodiaceae family is the most important cause of allergic re...

aspergillus species (a flavus and a niger) are important sources of inhalant allergens. current  diagnostic  modalities  employ  crude  aspergillus  extracts  which  only  indicate  the source to which the patient has been sensitized, without identifying the number and type of allergens in crude extracts. we report a study on the identification of major and minor allergens of the two common air...

background: allergens are mostly composed of glycoprotein structures. it is believed that glycan-specific antibodies may lead to false-positive reactions in immunoassays. in this study we investigated the glycosylation state of grape allergens as well as the presence of antibodies to cross-reactive carbohydrate determinants (anti-ccds) in sera from grape-sensitive individuals. methods: grape ex...

Background: Food hypersensitivity to walnut usually results in mild symptoms; however, several cases of anaphylactic reactions to this product have been observed. This study aimed to determine the immunochemical characteristics of the Persian walnut and provide the recombinant form of its main allergen. Materials and Methods: The allergenic proteins of th...