Celiac disease is a chronic illness of the small bowel caused by gliadin intolerance in genetically predisposed subjects. The aim of this study was to investigate serum levels of IgA and IgG antigliadin antibodies, IgA antiendomysial antibodies, and IgA anti-tissue transglutaminase antibodies in 169 patients with autoimmune thyroid diseases, i.e. chronic thyroiditis and Graves' disease. Antiend...

celiac disease has protean manifestations. in this report, a 24 year-old young female with celiac disease and acute lower extremity deep venous thrombosis (dvt) is presented. the patient was a 24 year-old female who presented with long standing diarrhea, 8 kg weight loss in the recent month, lower extremity edema, petechiae and purpura. laboratory exam demonstrated very high titers of iga antie...

The aim of the present study was to determine the prevalence of celiac disease in children of short stature and to assess whether some of the routine laboratory examinations performed to determine the cause of short stature could suggest the presence of celiac disease. A total of 106 children of short stature and no gastrointestinal symptoms were studied. An extensive endocrine work-up had been...

Coeliac disease is uncommon in childhood and diagnosed in fewer than 1 in 2500 children in the United Kingdom. Subclinical disease is, however, common in adults, and can be detected by testing for serum IgA antiendomysial antibodies (IgA-EMA). We aimed to establish the prevalence of undiagnosed coeliac disease in the general population at age seven, and to look for associated clinical features.

OBJECTIVE To study the frequency of positive serology for celiac disease (CD) in patients with duodenal biopsies suggestive of this disease. MATERIAL AND METHODS Cross sectional study. We included patients with duodenal biopsies histologically compatible with CD and antigliadin, antiendomysial and IgA antitransglutaminase antibodies. We defined a "case" of CD if there was a positive biopsy an...

BACKGROUND Coeliac disease is one of the commonest underdiagnosed diseases in general practice. The autoantigen recognised by the sera of patients with coeliac disease has recently been identified as tissue transglutaminase. AIMS We evaluated a simple non-invasive immunological dot blot assay for coeliac disease, suitable for use by the general physician in the ambulatory setting. The sensiti...

  Background and Objective: Celiac disease is an autoimmune disorder, characterized by inflammation, villous atrophy, and crypt hyperplasia of the small bowel mucosa. In this study we considered and compared sensitivity and specificity of serological tests in patients with celiac disease. Materials and Methods: In this cross-sectional study we prospectively recruited children with suspected c...

IgA nephropathy (IgAN) presents usually as a primary disease. However, secondary forms of IgAN have been described, most commonly associated with liver disease [1]. The presence of high levels of IgA against food antigens including gliadin and IgG and IgA antiendomysial antibodies in some patients with IgAN has raised the possibility of a pathophysiological link between IgAN and coeliac disease...

Celiac sprue is a disorder characterized by the symptoms of malabsorption and an abnormal small bowel histology, which is due to the patient's intolerance to gluten. Gluten is a protein found in wheat and wheat products. The typical symptoms of malabsorption include weight loss, abdominal distention, bloating, diarrhea and steatorrhea. However, the severity of the disease varies greatly among t...

BACKGROUND Literature data have shown high specificity of antiendomysial antibodies (EmA IgA) in celiac disease. The scarcity of Brazilian reports concerning this subject motivated the present study. OBJECTIVES To determine the sensitivity and specificity of antiendomysial IgA antibodies in Brazilian celiac patients at diagnosis and after treatment, to confirm patient adherence to a gluten-fr...