background: to determine the colon transit time (ctt) in patients complaining of functional constipation and to evaluate the correlation between abnormal transit times and the types of constipation and the correlation with age and sex. materials and methods: the signs and symptoms of 84 patients with infrequent or difficult defecation, 33 males and 51 females, with a median age of 33.7 were rec...

Linaclotide (Linzess) for irritable bowel syndrome with constipation and for chronic idiopathic constipation.

UNLABELLED The authors investigated 103 consecutive Thai patients (29M, 74F age 50 +/- 20) with chronic idiopathic constipation (symptom duration; median 5 yr, range 0.25-45 yr) as defined by Rome II criteria using colonic transit test, anorectal manometry, and balloon expulsion tests. Constipation symptoms were evaluated by a questionnaire. RESULTS There were 30, 14, 11, and 48 patients who ...

[Purpose] This study aimed to determine whether low-frequency current therapy can be used to reduce the symptoms of idiopathic slow transit constipation (ISTC). [Subjects] Fifteen patients (ten male and five female) with idiopathic slow transit constipation were enrolled in the present study. [Results] Bowel movements per day, bowel movements per week, and constipation assessment scale scores s...

OBJECTIVE Patients with idiopathic slow-transit constipation comprise a small proportion of the total population complaining of constipation. The purpose of this review is to present an update of pathophysiology of this disorder and its application in clinical management. METHODS Medline was used to search English language articles published up to the end of September 2002 on the subject of s...

BACKGROUND Constipation is one of the most common gastrointestinal disorders particularly in industrialized countries. Incidence of constipation varies from 3.4 % to 27.2% in different societies. Increase in urban population, industrialization of communities, changes in behavioral and nutritional habits and inactivity have increased the number of patients suffering from constipation. OBJECTIV...

PURPOSE This study aimed to evaluate the colorectal luminal transport obtained by retrograde colonic washout with a new scintigraphic technique. METHODS Nineteen patients (5 with spinal cord lesion, 6 with idiopathic fecal incontinence, and 8 with idiopathic constipation) treated with retrograde colonic washout took indium-111-labeled polystyrene pellets to label the bowel contents. Technetiu...

BACKGROUND Real-life data on the economic burden of chronic idiopathic constipation are scarce. The objectives of this study were to assess hospitalization resource use and costs associated with chronic constipation and its complications in Belgium. METHODS This was a single country, retrospective study using the IMS Hospital Disease Database (2008), which comprises data on 34% of acute hospi...

Constipation is a common symptom in patients of all ages, but its occurrence is highest among persons 65 years of age or older.1,2 Constipation has been shown to diminish both quality of life and feeling of well-being.3-5 Although constipation can have many causes, it is most often functional or idiopathic.5,6 Furthermore, constipation can lead to serious complications such as malnutrition, fec...