BACKGROUND An observational case series was used to study the virulence characteristics and genotypes of paired Staphylococcus epidermidis isolates cultured from intraocular samples and from periocular environment of patients with postcataract surgery endophthalmitis. METHODS Eight S. epidermidis isolates were obtained from three patients (2 from patients #1 and 2 and 4 from patient #3) whose...

The aim of this study was to investigate the presence of virulence genes in 46 coagulase-negative staphylococci (CNS) strains isolated from 46 udder quarters of 46 cows with subclinical mastitis. The isolates were examined phenotypically (cultural features, Gram stain, catalase, coagulase, API tests) and genotypically for: icaA, icaAB, icaD, atlE, bhp, agrA, sarA, mecA, and blaZ genes. These is...

Staphylococcus epidermidis is the most prevalent coagulase-negative Staphylococcus (CNS) and is a major cause of hospital bacteremia. Based on 18 reference strains and 149 Staphylococcus clinical strains, used in a novel multiplex PCR method, the aim of this study was to identify S. epidermidis with respect to the sequence of three genes: recN, which encodes a recombination/repair protein, mecA...

objective(s) methicillin-resistant staphylococcus aureus (mrsa) is an important cause of nosocomial and community infections. biofilm formation, mediated by a polysaccharide intercellular adhesin (pia) and encoded by the ica operon, is considered to be an important virulence factor in both s. epidermidis and s. aureus. however, the clinical impact of the ica locus and pia production is less wel...

Staphylococcus epidermidis is one of the most prevalent pathogens implicated in catheter-related bloodstream infections (CRBSI) at an academic hospital in Pretoria, South Africa. Little is known about the clonality and the prevalence of antibiotic resistance and virulence genes in S. epidermidis (e.g., icaAB, IS256, mecA, and qacA/B). A total of 508 intravascular catheters (IVCs) from 331 patie...

Infections caused by commensal organisms by changing to infectious life style generate much challenge to the current treatment strategies. Coagulase Negative Staphylococci (CoNS) are one of them, with their coexisting biofilm forming and multiple antibiotic resistance properties form important agents of nosocomial infection. To evaluate species distribution, biofilm formation, and antibiogram, ...

PURPOSE The clinical significance of many species belonging to coagulase-negative staphylococci (CoNS) other than Staphylococcus epidermidis has been increasingly recognized. The present study attempted the characterization of non-S. epidermidis CoNS isolates of ocular origin. METHODS The isolates were characterized phenotypically by analytical profile index (API) and genotypically by fluores...

Objective(s) Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of nosocomial and community infections. Biofilm formation, mediated by a polysaccharide intercellular adhesin (PIA) and encoded by the ica operon, is considered to be an important virulence factor in both S. epidermidis and S. aureus. However, the clinical impact of the ica locus and PIA production is less w...