Theresa I. Shireman, PhD; Kaijun Wang, PhD; Jeffrey L. Saver, MD; Mayank Goyal, MD; Alain Bonafé, MD; Hans-Christoph Diener, MD, PhD; Elad I. Levy, MD; Vitor M. Pereira, MD; Gregory W. Albers, MD; Christophe Cognard, MD; Werner Hacke, MD, PhD; Olav Jansen, MD, PhD; Tudor G. Jovin, MD; Heinrich P. Mattle, MD; Raul G. Nogueira, MD; Adnan H. Siddiqui, MD, PhD; Dileep R. Yavagal, MD; Thomas G. Devl...

In PNAS, Jahan et al. (1) describe a new role for the ubiquitin-specific protease 12 (USP12) deubiquitinase in T-cell receptor (TCR) signaling. Among other findings, the authors report that USP12 is exported from the nucleus to the cytosol upon TCR activation. Although the experimental evidence they provide is consistent with this model, I believe that some of their results would require a more...

Let I ⊂ K[x1, . . . , xn] be a zero-dimensional monomial ideal, and ∆(I) be the simplicial complex whose Stanley–Reisner ideal is the polarization of I. It follows from a result of Soleyman Jahan that ∆(I) is shellable. We give a new short proof of this fact by providing an explicit shelling. Moreover, we show that ∆(I) is even vertex decomposable. The ideal L(I), which is defined to be the Sta...

The Stanley’s Conjecture on Cohen-Macaulay multigraded modules is studied especially in dimension 2. In codimension 2 similar results were obtained by Herzog, Soleyman-Jahan and Yassemi. As a consequence of our results Stanley’s Conjecture holds in 5 variables.

Individual patient data meta-analysis of randomized trials of Solitaire stent thrombectomy Bruce C.V. Campbell MBBS PhD, Michael D. Hill MD MSc, Marta Rubiera MD, Bijoy K. Menon MD MSc, Andrew Demchuk MD, Geoffrey A. Donnan MD, Daniel Roy MD, John Thornton MD, Laura Dorado MD PhD, Alain Bonafe MD, Elad I. Levy, MD, Hans-Christoph Diener MD PhD, María Hernández-Pérez MD PhD, Vitor M. Pereira MD,...

Kallmann syndrome is a very rare hereditary disease. It is characterized by hypogonadotropic hypogonadism in association with anosmia ot hyposmia, both of which occur as a result of impairment of olfactory axon development and failure of migration of gonadotropin-releasing hormone (GnRH) neurons. Mode of inheritance can be autosomal dominant, autosomal recessive, or X-linked. We report a case o...

BANGLADESH, WITH AN estimated population of about 111 million, is one of the most densely populated countries in the world. In a predominantly rural economy, with a per capita income of US$ 220 about 48 per cent of rural and 44 per cent of the urban population live below the poverty line defined as 2122 calorie intake per person. Average households spend 59 per cent of their income on food, yet...

A long-standing conjecture of Stanley states that every Cohen– Macaulay simplicial complex is partitionable. We disprove the conjecture by constructing an explicit counterexample. Due to a result of Herzog, Jahan and Yassemi, our construction also disproves the conjecture that the Stanley depth of a monomial ideal is always at least its depth.