نتایج جستجو برای: hypothyroid

تعداد نتایج: 2540  

Journal: :The Journal of clinical investigation 1970
E W Holmes V A DiScala

The exaggerated natriuresis of hypothyroid rats receiving a 5% saline infusion was studied to determine the mechanism and the site within the nephron responsible for this increase in sodium excretion. Sodium clearance (C(Na)) and fractional sodium excretion were both demonstrated to be greater in hypothyroid rats for any amount of sodium infused. The rate of increase in fractional sodium excret...

Journal: :Annals of the rheumatic diseases 2010
H G Raterman I C van Eijk A E Voskuyl M J L Peters B A C Dijkmans V P van Halm S Simsek W F Lems M T Nurmohamed

OBJECTIVES Rheumatoid arthritis (RA) patients are at increased risk of cardiovascular disease (CVD), which is even more pronounced in hypothyroid RA patients. An unfavourable cardiovascular risk profile conferred by a higher prevalence of the metabolic syndrome (MetS) and a higher Framingham risk score might explain this amplified cardiovascular morbidity. This study compared first, MetS (featu...

Journal: :Cardiology journal 2012
Serkan Ozturk Oguz Dikbas Mehmet Ozyasar Selim Ayhan Fatih Ozlu Davut Baltaci Alim Erdem Aytekin Alcelik Mehmet Tosun Mehmet Yazici

BACKGROUND The aim of this study was to investigate left atrial (LA) mechanical functions, atrial electromechanical delay and P wave dispersion in hypothyroid patients. METHODS Thirty-four patients with overt hypothyroid and thirty controls were included. A diagnosis of overt hypothyroid was reached with increased serum TSH and decreased free T4 (fT4) levels. LA volumes were measured using th...

2014
Lai-Chu See Chang-Fu Kuo Kuang-Hui Yu Shue-Fen Luo I-Jun Chou Yu-Shien Ko Meng-Jiun Chiou Jia-Rou Liu

OBJECTIVES The aim of this study was to estimate the risk of hyperuricaemia and gout in people with hypothyroid or hyperthyroid status. METHODS This study analyzed data from individuals who participated in health screening programs at Chang Gung Memorial Hospital in northern Taiwan (2000-2010). Participants were categorized as having euthyroid, hypothyroid, or hyperthyroid status according to...

اسدمبینی, عاطفه , حصاری , مهوش , شکیبایی, داریوش, واعظی , مریم,

Background and Objective: Hypothyroidism decreases cardiac contractility and heart rate. Since cardiac function is also modulated by diazepam, the aim of this study was to investigate the direct effect of diazepam on the isolated hypothyroid rat heart. Materials and Methods: This experimental study was conducted on 30 rats in four groups (control, hypothyroid, control diazepam and hypotyroid+d...

 Backgrounds: Thyroid hormones play an important physiological role in human metabolism. Erythrocyte abnormalities are frequently associated with thyroid disorder. However, they are rarely investigated and related to the subclinical and primary hypothyroidism in Kashmiri Patients. In this study an attempt was made to study hematological parameters in untreated and treated subclinical hypothyroi...

Journal: :The American journal of physiology 1971
E W Holmes V A DiScala

HOLMES, EDWARD W., JR-, AND VINCENT A. DISCALA. Oxygen consumption, glycolysis, and sodium reabsorption in the hypothyroid rat kidney. Am. J. Physiol. 221(3) : 839-843. 1971.-Rates of oxygen consumption (Qog) and anaerobic glycolysis (Qco~) were determined in renal tissue slices from control and hypothyroid rats. Qcoz was 19 c/0 lower (I’ < 0.05) in tissue from the inner medulla of hypothyroid ...

Journal: :Japanese journal of pharmacology 1981
Y Hagino T Uematsu M Tachibana

Changes in the properties of cyclic AMP-dependent protein kinase were studied in the kidney of hypothyroid rats. The activity of the crude extract was greater in hypothyroid rats than in normal ones. The ratio of type I isozyme to type II isozyme in hypothyroid rats was about twice that in the normal rats with enzymes from both the cortex and medulla. A higher affinity for the substrates was sh...

Journal: :Sri Lanka Journal of Diabetes Endocrinology and Metabolism 2014

Journal: :American journal of physiology. Renal physiology 2004
Michel Baum Raymond Quigley

Proximal straight tubules (PST) from both neonatal and hypothyroid adult rabbits have a lower rate of passive volume absorption when perfused with a high-chloride solution simulating late proximal tubular fluid than adult rabbit PST. We hypothesized that the maturational increase in serum thyroid hormone levels mediates the developmental changes in PST paracellular permeability. Neonatal tubule...

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