scleromyxedema is a rare, chronic, progressive, fibromucinous disorder of unknown etiology, characterized by lichenoid waxy papules and firm induration of skin of trunk, face, forearm and hands; fibroblast proliferation and mucin deposition in the upper dermis. cutaneous involvement is characteristic but there are several associated systemic manifestations: we observed a case of scleromyxedema ...

Thyroid disorders are the most common endocrine disorders. In the present study 51 hypothyroid cases and 50 Euthyroid controls were analysed for Thyroid Profile, Lipid Profile, Body Mass Index (BMI) waist circumference, Hip circumference and waist hip ratio. Out of 51 Hypothyroid subjects studied, 5 are having subclinical Hypothyroidism, 20 are having mild Hypothyroidism, 14 Subjects are having...

Propylthiouracil (PTU)-induced hypothroidism has been shown to produce a significant increase in the uptake of radiophosphorus (““P) by the testes of young chicks. Continued investigation of this effect demonstrated that thyroidectomy of young birds resulted in elevations in testis 32P uptake comparable to those observed following the administration of PTU. It would thus appear that the increas...

The effect of TRH administration on serum GH was studied in 6 normal subjects, 13 patients with primary hypothroidism and 6 thyrotoxic subjects. Although no appreciable changes of serum GH were noted in the normal subjects, TRH administration provoked an increase of serum GH in 6 out of 13 patients with primary hypothyroidism. Serum GH levels in response to TRH administration were decreased in ...

Background: Vitiligo is a depigmenting disorder characterized by the loss of melanocytes. Thyroid functional disorders and autoimmune thyroid diseases have been reported in association with vitiligo. This study was thus conducted to find out any association of vitiligo with thyroid dysfunction. Methodology: This study was conducted at the Dermatology Department of a teaching medical college. Th...

BACKGROUND Heart rate turbulence (HRT) is a baroreflex-mediated biphasic reaction of heart rate in response to premature ventricular beats. Abnormal HRT identifies patients with autonomic dysfunction or impaired baroreflex sensitivity. The aim of the present study was to demonstrate the effect of subclinical hypothyroidism (SCH) on cardiac autonomic function using HRT parameters. METHODS The ...

We propose to establish the relationship between the clinical, functional and immunological parameters in a cohort of women with Hashimoto’s thyroiditis. The study included 68 patients between 19 and 70 who were hospitalized for two years in the Endocrinology Clinic of the Hospital in Timisoara. The thyroidal dimensions and the aspects of the thyroidal stroma were shown by echography examinatio...

disturbances in calcium metabolism and both impairment are some of the known complications observed in beta thalassemia major patients.although iron deposition has been recognized to be the main factor for organ dysfunction in these patients,the relatively low prevalence of hypoparathyroidism has led to giving more emphasis to Ca metabolism disturbance among others.availability of more patients...