Hypertrophic osteopathy (Marie’s disease) is a syndrome characterised by periosteal proliferation along the metaphyses and diaphyses proximal and distal to the joints of long bones classically associated with space-occupying lesions of the thorax (Butler et al. 1993). The syndrome is most frequently documented in human and canine patients (Brown et al. 1980), but has also been diagnosed infrequ...

209 Hypertrophic Osteopathy in Dogs INTRODUCTION Hypertrophic osteopathy (HO) is characterized by pathologic periosteal new bone formation (PNBF) (1). It occurs most commonly in humans and dogs, and has been described in other species (2, 3). It develops mostly secondary to various underlying conditions, classified as pulmonary, non-pulmonary intra-thoracic and extra-thoracic. Pulmonary patholo...

Background: Aortic thrombosis (ATh) is an uncommon problem in dogs. Although the pathogenesis of hypertrophic osteopathy (HO) is unknown, it is thought this can be due to blood flow disorder. In this case, removal of aortic thromboembolism (ATE) resulted in periosteal proliferation. Case description: A 4.8-kg, 3-year-old, intact female Maltese was referred with...

A five-year-old dog was referred with a five-month history of lethargy, decreased appetite, cough and intermittent forelimb lameness. Radiographs revealed an intra-thoracic lesion and a marked periosteal bone apposition of the second digit on the left forelimb. As it was palisading and circumferential, the latter appeared typical of hypertrophic osteopathy (HO). A grass awn in a sub-lobar ramif...

A 6-year-old male, Belgian shepherd dog was presented with lethargy, oliguria, hematuria, and reluctance to move. The dog developed hypertrophic osteopathy secondary to renal pelvis transitional cell carcinoma. A nephrectomy was performed and after a year, the dog was completely asymptomatic, and no evidence of metastatic disease was present.