We studied the effects of 2 different dosages of highmolecular- weight poly-γ-glutamic acid (hm γ-PGA) derived from Bacillus subtilis chungkookjang on lipid metabolism in a high-fructose diet-induced hypertriglyceridemic animal model. For 4 weeks, rats were fed either AIN-93 diet (normal control, NC; n = 10) or modified AIN-93 diet in which cornstarch was substituted with 63% fructose (n = 30) ...

Triglyceride-rich lipoproteins may be responsible for the lipid accumulation in macrophages that can occur in hypertriglyceridemia. Chylomicrons and very low density lipoproteins (VLDL, total and with flotation constant [S(f)] 100-400) from fasting hypertriglyceridemic subjects induced a massive accumulation of oil red O-positive inclusions in unstimulated peritoneal macrophages. Cell viability...

This Article contains typographical errors in the Discussion section. " Our previous study 8 had proven that the local high concentration of free fatty acids in hypertriglyceridemic mice resulted in increased susceptibility to acute pancreatitis. We also had found enhanced susceptibility to acute pancreatitis in hypertriglyceridemic Syrian golden hamsters 26. " should read: " Our previous study...

In cholesterol-fed rabbits, alloxan-diabetes has an anti-atherogenic effect, which is associated with severe elevation of plasma triglyceride concentrations. To study this effect, we measured lipoprotein sizes and aortic permeability coefficients for cholesteryl ester and for albumin in hypertriglyceridemic diabetic cholesterol-fed rabbits and in normotriglyceridemic cholesterol-fed rabbits. Wi...

Normotriglyceridemic and hypertriglyceridemic samples were analyzed for apoproteins A-I and B using the Beckman Array System and the Behring Nephelometer, and the nephelometric values were compared to values obtained by highly standardized radioimmunoassays developed at the Northwest Lipid Research Center. Although the means of the apoA-I values obtained by each method were similar, comparison ...

Using the hypertriglyceridemic recall group of the Princeton School Family Study, we assessed the effectiveness and ramifications of family sampling based on hypertriglyceridemic probands and examined whether within-family correlations of lipids and lipoproteins outlast the period of shared common household environments. Thirty-two pediatric and 35 adult probands (who had fasting plasma triglyc...

Using the hypertriglyceridemic recall group of the Princeton School Family Study, we assessed the effectiveness and ramifications of family sampling based on hypertriglyceridemic probands and examined whether within-family correlations of lipids and lipoproteins outlast the period of shared common household environments. Thirty-two pediatric and 35 adult probands (who had fasting plasma triglyc...

Background—The present study tested the hypothesis that simple variables, such as waist circumference and fasting plasma triglyceride (TG) concentrations, could be used as screening tools for the identification of men characterized by a metabolic triad of nontraditional risk factors (elevated insulin and apolipoprotein [apo] B and small, dense LDL particles). Methods and Results—Results of the ...