Dehydration in the neonatal period has many causes. Dehydration is classified as isotonic, hypotonic, or hypertonic, based on the serum osmolality that in most cases is reflected in the serum sodium level. Hypernatremic dehydration is usually caused by gastroenteritis, but it can also be caused by salt poisoning or diabetes insipidus. This type of dehydration can be especially dangerous. The hy...

OBJECTIVE To assess any relationship between serum sodium changes and seizure occurrence in children aged 2 months to 5 years with hypernatremic dehydration. MATERIALS & METHODS This cross-sectional study was performed on 63 patients aged 2 months to 5 years from 20 March 2006 to 15 March 2012 at Ghaem Hospital and Dr. Sheikh Hospital in Mashhad, Iran. Patients were divided into 2 groups: cas...

BACKGROUND Hypernatremic dehydration in neonates is a potentially devastating condition. Recent reports have identified breast-feeding malnutrition as a key factor in its pathophysiology. METHODS Using a theoretical framework for breast-feeding kinetics, a retrospective chart review of all neonates less than 28 days of age who were seen at either British Columbia's Children's Hospital or the ...

Background In breast-fed neonates, hypernatremia may occur from inadequate breast milk production, central or nephrogenic diabetes insipidus, gastroenteritis, or salt poisoning. Hypernatremic dehydration is a known risk factor for cerebral sinus thrombosis and death. We report a breastfed neonate with hypernatremic dehydration, diabetes insipidus, cerebral sinus thrombosis, and disseminated int...

BACKGROUND Neonatal hypernatremic dehydration is prevented by daily neonatal weight monitoring. We aim to provide evidence-based support of this universally promoted weighing policy and to establish the most crucial days of weighing. METHODS Weight measurements of 2,359 healthy newborns and of 271 newborns with clinical hypernatremic dehydration were used within the first seven days of life t...

OBJECTIVES To assess the incidence and complications of breastfeeding-associated hypernatremic dehydration among hospitalized neonates. STUDY DESIGN A retrospective study was conducted at Children's Hospital of Pittsburgh over a 5-year period, to identify otherwise healthy term and near-term (> or =35 weeks of gestation) breastfed neonates (<29 days of age) who were admitted with serum sodium...

Inadequate breastfeeding may result in malnutrition, hypernatremic dehydration and catastrophic outcomes. We describe a case of severe breast feeding associated hypernatremia which was complicated by acute seizures and severe hyperglycemia. The baby's condition was initially confused with neonatal diabetes mellitus.