Introduction: This study aimed to assess the incidence of breastfeeding-associated hypernatremia and related risk factors among hospitalized hyperbilirubinemic neonates. Methods: This prospective study was conducted at Nemazee Hospital affiliated to Shiraz University of Medical Sciences during one year to determine the association between hypernatremia (serum sodium concentration of >150 mEq/L)...

PURPOSE The purpose of this study is to examine the impact of hypernatremia acquired after intensive care unit (ICU) admission on mortality and length of stay (LOS). MATERIALS AND METHODS Data for this observational study were collected from patients admitted between January 1, 2008, and September 30, 2010 to 344 ICUs in the eICU Research Institute. RESULTS Of the 207702 eligible patients, ...

BACKGROUND Hypernatremia has been associated with substantial morbidity and death in human patients. The incidence and importance of hypernatremia in dogs and cats has not been determined. HYPOTHESIS/OBJECTIVES To describe the incidence of and prognosis associated with hypernatremia in dogs and cats at a university teaching hospital. ANIMALS A total of 16,691 dogs and 4,211 cats with measur...

Organs from hypernatremia (elevated Na+) donors when used for transplantation have had dismal outcomes. However, islet isolation from hypernatremic donors for both transplantation and research applications has not yet been investigated. A retrospective analysis of in vivo and in vitro islet function studies was performed on islets isolated from hypernatremic (serum sodium levels≥160 meq/l) and ...

Background: Traumatic Brain Injury (TBI) causes a severe toll on society. TBI is a leading cause of mortality and morbidity worldwide, and the major cause of disability among children and young adults. Material and Methods: This study was conducted on 90 patients of both sexes with diagnosis of severe TBI presented to the Emergency Department (ER) and Critical Care Medicine Department, Faculty ...

Hypernatremia in the geriatric population is a common disorder associated with significant morbidity and mortality. Older people are predisposed to developing hypernatremia because of age-related physiologic changes such as decreased thirst drive, impaired urinary concentrating ability, and reduced total body water. Medications may exacerbate this predisposition. Hypernatremia and dehydration o...

BACKGROUND Hypernatremia is common following traumatic brain injury (TBI) and occurs from a variety of mechanisms, including hyperosmotic fluids, limitation of free water, or diabetes insipidus. The purpose of this systematic review was to assess the relationship between hypernatremia and mortality in patients with TBI. METHODS We searched the following databases up to November 2012: MEDLINE,...

INTRODUCTION Hypernatremia is a common problem in hospitalized patients and is associated with high morbidity and mortality. This study was designed to evaluate whether physicians follow the recommended guidelines for the rate of correction of hypernatremia of ≤0.5 mEq/L/hr and to evaluate the effect of the rate of correction of severe hypernatremia on the mortality of hospitalized patients. ...

Hyponatremia and hypernatremia are complex clinical problems that occur frequently in full term newborns and in preterm infants admitted to the Neonatal Intensive Care Unit (NICU) although their real frequency and etiology are incompletely known. Pathogenetic mechanisms and clinical timing of hypo-hypernatremia are well known in adult people whereas in the newborn is less clear how and when hyp...