Studies of platelet and fibrinogen kinetics in 27 patients with hyperlipoproteinemia and 28 control subjects demonstrated shortened platelet survival and increased platelet turnover in seven patients with type III and 10 patients with type IV-V hyperlipoproteinemia (p less than 0.01). There was no correlation between platelet survival time and specific lipid levels, vascular disease, sex or age...

BackgroundLipoprotein lipase (LPL) is an important enzyme in lipid metabolism, individuals with LPL variants could present type I hyperlipoproteinemia, lipemia retinalis, hepatosplenomegaly, and pancreatitis. To date, there are no reports of renal lipidosis induced by hyperlipoproteinemia due to mutation.MethodsRenal biopsy was conducted confirm the etiological factor nephrotic syndrome a 44-ye...

c3 typing was performed, by agarose gel electrophorisis, in 147 german patients suffering from hyperlipoproteinemia. the control group consisted of 322 healthy germans. high frequencies of non-typeable sera, varying between 16.66 and 35.71% in different hlp types, found in the present investigation are notable and are a clue for chemical denaturation of c3 protein in hlp patients. statistical a...

The relationship between a certain form of type 2 diabetes mellitus and familial endogenous hyperlipoproteinemia still remains confused. Therefore, we examined glucose tolerance and insulin secretion in 133 members (6-80 years old) of 15 families with a history of endogenous hyperlipoproteinemia. A segregation study was carried out to compare the prevalence of diabetes in hyperlipoproteinemic a...

in this report, a 10 year old boy with both tendinous and tuberous xanthoma is presented. premature corneal arcus and aortic stensosis were associated findings in this case. tuberous and tendinous xanthomas are two clinical varieties of one disease, both of which are seen in type ii hyperlipoproteinemia. increased serum cholesterol with pathological findings of skin lesions with oculocardiac in...

men at comparable ages. Hyperlipoproteinemia, cholesterol, and triglyceride elevations were more common in MI patients than in men in the random sample, occurring with greatest frequency in the younger patients. There was a trend toward higher mortality among patients with hyperlipoproteinemia. Types II A and B were very common in young patients. Serum cholesterol values were significantly high...

SUMMARY The prevalence of five types of hyperlipoproteinemia identified by Fredrickson, Levy, and Lees has been identified in 1301 male and female blood donors, aged 18-64 years. No patients with type I or V hyperlipoproteinemia were encountered, and only three patients with type III hy-perlipoproteinemia were discovered. Type IV hyperlipoproteinemia was the most prevalent disorder in this popu...