the present study investigates the antioxidant, anticancer, anticholinesterase, anti-genotoxic activities and phenolic contents of flower, fruit and seed methanol extracts of hypericum retusum aucher. the amounts of protocatechuic acid, catechin, caffeic acid and syringic acid in methanol extracts were determined by hplc. total phenolic content of h. retusum seed extract was found more than fru...

The present study investigates the antioxidant, anticancer, anticholinesterase, anti-genotoxic activities and phenolic contents of flower, fruit and seed methanol extracts of Hypericum retusum AUCHER. The amounts of protocatechuic acid, catechin, caffeic acid and syringic acid in methanol extracts were determined by HPLC. Total phenolic content of H. retusum seed extract was found more than fru...

The present study investigates the antioxidant, anticancer, anticholinesterase, anti-genotoxic activities and phenolic contents of flower, fruit and seed methanol extracts of Hypericum retusum AUCHER. The amounts of protocatechuic acid, catechin, caffeic acid and syringic acid in methanol extracts were determined by HPLC. Total phenolic content of H. retusum seed extract was found more than fru...

The present study investigates the antioxidant, anticancer, anticholinesterase, anti-genotoxic activities and phenolic contents of flower, fruit and seed methanol extracts of Hypericum retusum AUCHER. The amounts of protocatechuic acid, catechin, caffeic acid and syringic acid in methanol extracts were determined by HPLC. Total phenolic content of H. retusum seed extract was found more than fru...

Hypericum perforatum is known to have diverse medicinal uses for centuries. The antidepressant activity of Hypericum perforatum is widely accepted and proved in both animal and clinical studies. Present study was undertaken to investigate the effect of Hypericum perforatum in a battery of animal models for metabolic disorder. Hypericum is tested for hypolipidemic activity in normal rats, antiob...

MAIN RESULTS Thirty five published RCTs met criteria for inclusion in the review (24 trials comparing hypericum extracts with placebo, seven comparing hypericum extracts with older antidepressants, and six comparing hypericum with selective serotonin reuptake inhibitors (SSRIs)). Compared with placebo, hypericum resulted in similar numbers of dropouts due to adverse effects (24 RCTs, 8/1334 (0....

In this presentation I first review new developments of deontic logic in computer science, then I discuss the use of dynamic epistemic deontic logic to reason about privacy policies, and finally I discuss the use of modal logic for access control. This presentation is based on joint work with Guillaume Aucher, Guido Boella, Jan Broersen, Dov Gabbay and Valerio Genovese.

BACKGROUND Extracts of Hypericum perforatum (St John's wort) are widely used to treat depression. Evidence for its efficacy has been criticised on methodological grounds. AIMS To update evidence from randomised trials regarding the effectiveness of Hypericum extracts. METHODS We performed a systematic review and meta-analysis of 37 double-blind randomised controlled trials that compared cli...

Extracts of Hypericum, Passiflora and Valeriana are used for the treatment of mild depression and anxiety. We were interested whether a combination of Hypericum and Passiflora exerts comparable effects to Hypericum alone. We used two well-established models for investigating extracts for their anti-depressant activity, namely the effects on synaptic uptake of serotonin and the forced-swimming-t...

Observations: Hypericin, originating from Hypericum perforatum, is a potent photosensitizer known to induce skin phototoxicity when given systemically. Hypericum perforatum is a botanical extracts with anti-inflammatory and antibacterial effect. Photocontact dermatitis is a common cutaneous reaction by various herbs. We describe a 54-year-old female patient with Hypericum perforatum associated ...