نتایج جستجو برای: hypericins

تعداد نتایج: 25  

Journal: :Acta poloniae pharmaceutica 2010
Małgorzata Anyzewska Anna Kowalczuk Anna Łozak Renata Jabłczyńska Zbigniew Fijałek

The work aimed to determine the levels of hypericins expressed as hypericin in the herbal substance of St. John's wort, in capsules and tablets containing the extract of St. John's wort, tablets containing powdered herb and in tincture and juice from fresh St. John's wort, by HPLC method with spectrophotometric detection. In addition, the amount of hypericins in the infusion prepared from St. J...

Journal: :International Journal of Molecular Sciences 2010

2010
Anastasia Karioti Anna Rita Bilia

70 years have passed since the first isolation of the naphthodianthrones hypericin and pseudohypericin from Hypericum perforatum L. Today, they continue to be one of the most promising group of polyphenols, as they fascinate with their physical, chemical and important biological properties which derive from their unique chemical structure. Hypericins and their derivatives have been extensively ...

Journal: :iranian journal of pharmaceutical research 0
cuneyt cirak ondokuz mayis university, vocational high school of bafra, samsun, turkey jolita radusiene nature research centre, institute of botany, zaliuju ezeru 49, vilnius lt 08406 liudas ivanauskas medical academy, lithuanian university of health sciences, a. mickeviciaus 9, kaunas lt 44307, lithuania valdas jakstas medical academy, lithuanian university of health sciences, a. mickeviciaus 9, kaunas lt 44307, lithuania necdet çamaş ondokuz mayis university, vocational high school of bafra, samsun, turkey

in the present study, we investigated the variation in the content of naphthodianthrones hypericin and pseudohypericin, phloroglucinol derivatives hyperforin and adhyperforin, the phenolic acids as chlorogenic acid, neochlorogenic acid, 2,4-dihydroxybenzoic acid, and the flavonols, namely, hyperoside, isoquercitrin, quercitrin, quercetin, avicularin, rutin, (+)-catechin and (-)-epicatechin, and...

Journal: :Jundishapur Journal of Natural Pharmaceutical Products 2017

Journal: :Journal of agricultural and food chemistry 2006
Laura A Schmitt Yi Liu Patricia A Murphy Diane F Birt

Hypericum perforatum (Hp) is known for possessing antidepressant and antiviral activities. Despite its use as an alternative to conventional antidepressants, the identification of the cytotoxic chemicals derived from this herb is incomplete. In this study, the cytotoxicity of Hp extracts prepared in solvents ranging in polarity, fractions of one extract, and purified compounds were examined in ...

Journal: :Biological research 2011
Giancarlo A Statti Filomena Conforti Federica Menichini Mariangela Marrelli Carmen Gangale Rosa Tundis Monica R Loizzo Marco Bonesi Francesco Menichini

The present study shows for the first time the phenolic composition and the in vitro properties (antioxidant and inhibition of nitric oxide production) of Hypericum calabricum Sprengel collected in Italy. The content of hypericins (hypericin and pseudohypericin), hyperforin, flavonoids (rutin, hyperoside, isoquercetrin, quercitrin, quercetin and biapigenin) and chlorogenic acid of H. calabricum...

2010
Ludger Beerhues

Extracts from Hypericum perforatum (St. John’s wort; Clusiaceae) are widely used for the treatment of mild to moderate depression. Four classes of constituents – hyperforins, hypericins, flavonoids, and xanthones – appear to contribute to the antidepressant activity. Interestingly, all four classes of secondary metabolites involve polyketide derivatives. Key reactions of their biosyntheses are ...

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