Hypercoagulability can be defined as the tendency to have thrombosis as a result of certain inherited and/or acquired molecular defects. Clinical manifestations of hypercoagulability can be devastating and even lethal. In the past 20 years, the origin of most of these diverse hypercoagulability syndromes has been elucidated. Currently, hypercoagulability disorders can be correctly diagnosed in ...

OBJECTIVES To investigate the prevalence of preoperative hypercoagulability assessed by thromboelastography (TEG), to identify patient characteristics associated with hypercoagulability and to explore whether hypercoagulability is associated with a greater risk for myocardial infarction (MI), stroke and mortality 30 days after coronary artery bypass grafting (CABG) surgery. METHODS This is a ...

INTRODUCTION Sepsis activates the coagulation system and frequently causes hypercoagulability, which is not detected by routine coagulation tests. A reliable method to evaluate hypercoagulability is thromboelastography (TEG), but this has not so far been used to investigate sepsis-induced hypercoagulability. Antithrombin (AT) in plasma of septic patients is decreased, and administration of AT m...

• A reliable and sensitive test for both hypoand hypercoagulability would be very desirable for clinical and research purposes. Rapid detection of hypercoagulability would be of value in conditions such as spontaneous clotting fluctuations which occur during stress in patients with congenital or acquired valvular heart diseases < and with previous myocardial infarction. It is difficult to find ...

INTRODUCTION Data on the incidence of a hypercoagulable state in trauma, as measured by thromboelastometry (ROTEM), is limited and the prognostic value of hypercoagulability after trauma on outcome is unclear. We aimed to determine the incidence of hypercoagulability after trauma, and to assess whether early hypercoagulability has prognostic value on the occurrence of multiple organ failure (MO...

• A reliable and sensitive test for both hypoand hypercoagulability would be very desirable for clinical and research purposes. Rapid detection of hypercoagulability would be of value in conditions such as spontaneous clotting fluctuations which occur during stress in patients with congenital or acquired valvular heart diseases < and with previous myocardial infarction. It is difficult to find ...