نتایج جستجو برای: hypercholesterolaemia

تعداد نتایج: 1774  

Journal: :European journal of preventive cardiology 2016
Liv Mundal Marit B Veierød Thomas Halvorsen Kirsten B Holven Leiv Ose Per Ole Iversen Grethe S Tell Trond P Leren Kjetil Retterstøl

Background Familial hypercholesterolaemia increases the risk for cardiovascular disease. The primary aim of the present study was to describe sex differences in incidence and prevalence of cardiovascular disease leading to hospitalisation in a complete cohort of genotyped familial hypercholesterolaemia patients. Design and methods In this registry study data on 5538 patients with verified genot...

2017
Ivan Pećin Merel L Hartgers G Kees Hovingh Ricardo Dent Željko Reiner

Familial hypercholesterolaemia is an autosomal dominant inherited disorder characterised by elevated low-density lipoprotein cholesterol levels and consequently an increased risk of atherosclerotic cardiovascular disease (ASCVD). Familial hypercholesterolaemia is relatively common, but is often underdiagnosed and undertreated. Cardiologists are likely to encounter many individuals with familial...

Journal: :Clinical science 1997
K C YU D Smith A Yamamoto A Kawaguchi M Harada-Shiba T Yamamura J C Mamo

1. Familial hypercholesterolaemia is a common genetic abnormality in man characterized by premature atherogenesis as a consequence of disturbed lipoprotein metabolism. Chylomicrons, which represent intestinally derived lipoproteins, are cleared poorly in familial hypercholesterolaemia which may explain the increased retention of chylomicron remnants in arterial fatty lesions. However, cellular ...

Journal: :Journal of clinical pathology 1961
J N HARRIS-JONES D J WARD

An association of essential hypercholesterolaemia and diabetes mellitus is postulated. Case records are included to illustrate hypercholesterolaemia secondary to acute diabetes mellitus, and essential hypercholesterolaemia, independent of, but accompanying diabetes mellitus. Whereas in the former the serum cholesterol returns to normal and its attendant clinical manifestations resolve when the ...

Journal: :The lancet. Diabetes & endocrinology 2016
Raul D Santos Samuel S Gidding Robert A Hegele Marina A Cuchel Philip J Barter Gerald F Watts Seth J Baum Alberico L Catapano M John Chapman Joep C Defesche Emanuela Folco Tomas Freiberger Jacques Genest G Kees Hovingh Mariko Harada-Shiba Steve E Humphries Ann S Jackson Pedro Mata Patrick M Moriarty Frederick J Raal Khalid Al-Rasadi Kausik K Ray Zelijko Reiner Eric J G Sijbrands Shizuya Yamashita

Familial hypercholesterolaemia is common in individuals who had a myocardial infarction at a young age. As many as one in 200 people could have heterozygous familial hypercholesterolaemia, and up to one in 300 000 individuals could be homozygous. The phenotypes of heterozygous and homozygous familial hypercholesterolaemia overlap considerably; the response to treatment is also heterogeneous. In...

رایانی, محمد , فخرزاده, حسین , نبی‎پور, ایرج , وثیق, علیرضا ,

Background: We estimated the prevalence of angina pectoris (AP) and myocardial infarction (MI) in the hyperlipidaemic population of Bushehr using the ROSE questionnaire and ECG changes using the Minnesota code. Methods: 1036 residents of Bushehr (in southern Iran), aged 30-64 years, were enrolled as part of a 2-year cross-sectional prevalence study of diabetes mellitus and other risk factors fo...

Journal: :Journal of the Royal Society of Medicine 1987

Journal: :Folia Cardiologica 2021

Angiopoietin-like proteins (ANGPTL) are a family of several proteins, which ANGPTL3, 4 and 8 involved in lipid metabolism. These discovered relatively recently, regulate the availability triglycerides for heart, skeletal muscles white brown adipose tissue depending on nutritional status body, thus contributing to maintenance energy homeostasis. gene mutations associated with significant reducti...

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