primary hyperaldosteronism is one of the few causes of hypertension that can be cured by surgery. primary hyperaldosteronism is caused by adrenocortical adenoma or hyperplasia. it is important to differentiate between adrenal adenoma and hyperplasia because the preferred treatments are different. in all patients with new-onest or worsening hypertension the primary hyperaldosteronism should be c...

BACKGROUND Results of several studies published since 1999 suggest that primary hyperaldosteronism (also known as Conn's syndrome) affects more than 10% of people with hypertension; however, such a high prevalence has also been disputed. Experts generally agree that resistant hypertension has the highest prevalence of primary hyperaldosteronism, on the basis of small studies. We aimed to assess...

INTRODUCTION AND OBJECTIVES Primary hyperaldosteronism is the most common cause of secondary hypertension. Elevated aldosterone levels cause heart damage and increase cardiovascular morbidity and mortality. Early diagnosis could change the course of this entity. The objective of this report was to study the clinical characteristics, cardiac damage and cardiovascular risk associated with primary...

normotensive hyperaldosteronism is a rare disorder. it is usually diagnosed with hypokalemia or an adrenal mass. our patient was a 27-year-old female presented with weakness. she had normal blood pressure, hypokalemia, high plasma aldosterone level and suppressed plasma renin activity. after the saline load, test aldosterone didn’t show suppression. adrenal computed tomography revealed a left a...

Recent reports suggesting that the prevalence of primary hyperaldosteronism may be higher than historically thought have relied on an elevated plasma aldosterone concentration/plasma renin activity ratio to either diagnose or identify subjects at high risk of having primary hyperaldosteronism and have not included suppression testing of all evaluated subjects. In this prospective study of 88 co...

Rhabdomyolysis may be secondary to trauma, excessive muscle activity, hereditary muscle enzyme defects and other medical causes. Primary hyperaldosteronism is characterised by hypertension, hypokalemia, suppressed plasma renin activity, and increased aldosterone excretion. Rhabdomyolysis is not common in primary hyperaldosteronism. We report here a 42-year-old woman presenting with rhabdomyolys...

OBJECTIVES To estimate the point prevalence of primary hyperaldosteronism in a government out-patient setting and to compare associated patient characteristics with those having essential hypertension. DESIGN Case series with external comparison. SETTING A single public hospital (Caritas Medical Centre) and all five associated general out-patient clinics in Sham Shui Po district in Hong Kon...

BACKGROUND An association between chronic hyperaldosteronism and medullary nephrocalcinosis has rarely been made, with only a handful of cases described in literature. CASE REPORT We describe five cases of hyperaldosteronism with a long- standing history in whom associated medullary nephrocalcinosis was established. CONCLUSIONS We infer that a chronic hyperaldosteronic status, whether prima...