نتایج جستجو برای: hyoscine
تعداد نتایج: 413 فیلتر نتایج به سال:
Safety index (S.I.) of ether, chloroform and halothane was determined in mice following premedication with chloral hydrate, phenobarbitone, diazepam and trifluoperazine given alone or in combination with atropine or hyoscine. The S.I. of ether was significantly raised by chloral hydrate and phenobarbitone when combined with atropine while trifluoperazine in combination with atropine or hyoscine...
The effect of hyoscine butylbromide (scopolamine butylbromide), a competitive nonselective antagonist of acetylcholine at muscarinic receptors, on the isolated rabbit duodenum, ileum and colon was investigated. Hyoscine butylbromide (9×10M 9×10M) decreased in a concentration-dependent manner the amplitude of the spontaneous pendular movements of the rabbi-isolated duodenum (r=0.99; p<0.001), il...
OBJECTIVES: The removal of pre-malignant colorectal lesions prevents cancer. Hyoscine has been proposed as a means of improving diagnosis by reducing colonic movements. The aim of this study was to analyze whether this anti-spasmodic enhances the detection of pre-malignant colorectal lesions. METHODS: In a randomized, double-blinded fashion patients received hyoscine or a saline solution in a...
BACKGROUND Prolonged labor is one of the most important risk factors for perinatal compromise and, if caused by obstructed labor, it carries the risk of uterine rupture, postpartum hemorrhage (PPH), puerperal sepsis, and maternal death. OBJECTIVE To determine whether or not hyoscine butylbromide shortens the stages of labor, without an increase in maternal or neonatal complications. METHOD ...
BACKGROUND Patients with acute renal colic usually require immediate diagnosis and treatment. In this clinical trial analgesic effect of hyoscine N-butyl bromide and desmopressin combination in comparison with hyoscine N-butyl bromide alone in patients with acute renal colic induced by urinary stones was assessed. METHODS The study included 114 patients randomly allocated in two groups (A and...
BACKGROUND AND AIM Postoperative catheter-related bladder discomfort (CRBD) can be a distressing complication for patients in whom a urinary catheter was inserted intraoperatively and is accompanied with patients' dissatisfaction. This trial investigated the efficacy of hyoscine and ketamine on treatment of postoperative CRBD in patients undergoing various surgeries. MATERIAL AND METHODS This...
OBJECTIVE Investigate whether hyoscine patch or glycopyrronium liquid is more effective and acceptable to treat drooling in children with neurodisability. DESIGN Multicentre, single-blind, randomised controlled trial. SETTING Recruitment through neurodisability teams; treatment by parents. PARTICIPANTS Ninety children with neurodisability who had never received medication for drooling (55...
AIMS Hyoscine (scopolamine), which is effective in the prophylaxis of motion sickness, shows similar binding affinities to all of the five known muscarinic receptor sub-types. The effectiveness of hyoscine was compared with zamifenacin (UK-76654), which binds selectively to the muscarinic M3 and m5 receptors. METHODS Eighteen subjects received hyoscine hydrobromide 0.6 mg, zamifenacin 20 mg, ...
Lorazepam 2 and 4 mg alone and in combination with atropine 0.4 mg and hyoscine 0.4 mg were studied as i.v. surgical premedicants in 150 patients. Relief of anxiety, sedation, patient acceptance, lack of recall and side-effects were evaluated. Hyoscine was found to improve the relief of anxiety and sedation associated with lorazepam, but did not significantly increase lack of recall or patient ...
A standard operative procedure and anaesthetic technique were employed to compare the effects of 0.6 mg atropine and 0.4 mg hyoscine, given as part or all of premedication, on the course of thiopentone anaesthesia. The incidence and severity of muscle movement following induction was increased by the use of hyoscine, but not to the same extent as previously found with methohexitone. This effect...
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