نتایج جستجو برای: hydroxydopamine rotational behavior motor imbalance dose

تعداد نتایج: 1114292  

Journal: :journal of basic and clinical pathophysiology 0
siamak afshin-majd neurophysiology research center, shahed university, tehran, iran mohsen khalili neurophysiology research center, shahed university, tehran, iran zahra kiasalari neurophysiology research center, shahed university, tehran, iran batool rahmati neurophysiology research center, shahed university, tehran, iran manijeh karami neurophysiology research center, shahed university, tehran, iran gholamhossein ghaedi neurophysiology research center, shahed university, tehran, iran tourandokht baluchnejadmojarad

background and objective: parkinson's disease (pd) is a neurodegenerative disease with selective damage of mesencephalic dopaminergic neurons. due to the protective, anti-inflammatory, and antioxidant effect of hypericum perforatum (hp), this study was undertaken to assess dose-dependent effect of hp hydroalcoholic extract on motor imbalance following intrastriatal injection of 6-hydroxydo...

Background and Objective: Parkinson's disease (PD) is a neurodegenerative disease with selective damage of mesencephalic dopaminergic neurons. Due to the protective, anti-inflammatory, and antioxidant effect of Hypericum perforatum (HP), this study was undertaken to assess dose-dependent effect of HP hydroalcoholic extract on motor imbalance following intrastriatal injection of 6-hydroxydopamin...

ژورنال: دانشور پزشکی 2015
افشین مجد, سیامک, خلیلی , محسن, رحمتی, بتول, روغنی, مهرداد, قائدی, غلامحسین, کرمی, منیژه, کیاسالاری, زهرا,

Background and Objective: Parkinson's disease is a rather common movement disorder in aged individuals due to degeneration of dopaminergic neurons within the substantia nigra pars compacta. Due to antioxidant, anti-inflammatory and protective effects of the flavanone hesperetin, the present study assessed dose-dependent effect of hesperetin on motor asymmetry induced by intrastriatal injection ...

Journal: :journal of basic and clinical pathophysiology 2015
tourandokht baluchnejadmojarad monireh mansouri farnaz nikbakht soudabeh fallah mehrdad roghani

background and objective: parkinson's disease (pd) is an age-related neurodegenerative disease with selective damage of dopaminergic neurons of the mesencephalon. l-dihydroxyphenylamine (l-dopa) therapy is currently the gold standard maneuver for pd. due to the protective, anti-inflammatory, and antioxidant effect of sesamin, this study was undertaken to assess dose-dependent effect of this age...

Journal: :journal of basic and clinical pathophysiology 0
tourandokht baluchnejadmojarad department of physiology, school of medicine, iran university of medical sciences, tehran, iran monireh mansouri department of physiology, school of medicine, iran university of medical sciences, tehran, iran farnaz nikbakht department of physiology, school of medicine, iran university of medical sciences, tehran, iran soudabeh fallah department of biochemistry, school of medicine, iran university of medical sciences, tehran, iran mehrdad roghani neurophysiology research center, shahed university, tehran, iran

background and objective: parkinson's disease (pd) is an age-related neurodegenerative disease with selective damage of dopaminergic neurons of the mesencephalon. l-dihydroxyphenylamine (l-dopa) therapy is currently the gold standard maneuver for pd. due to the protective, anti-inflammatory, and antioxidant effect of sesamin, this study was undertaken to assess dose-dependent effect of thi...

Farnaz Nikbakht, Mehrdad Roghani, Monireh Mansouri, Soudabeh Fallah Tourandokht Baluchnejadmojarad

Background and Objective: Parkinson's disease (PD) is an age-related neurodegenerative disease with selective damage of dopaminergic neurons of the mesencephalon. L-dihydroxyphenylamine (L-DOPA) therapy is currently the gold standard maneuver for PD. Due to the protective, anti-inflammatory, and antioxidant effect of sesamin, this study was undertaken to assess dose-dependent effect of this age...

Journal: :journal of basic and clinical pathophysiology 2015
batool rahmati mohsen khalili zohreh hamoleh-shalali mehrdad roghani tourandokht baluchnejadmojarad

background and objective: parkinson's disease (pd) is a movement disorder with debilitating symptoms. available treatments for pd mainly include its symptomatic relief with no prevention of its progression. due to the iron-chelating and antioxidant effect of phytic acid (pa), this study was conducted to assess its protective effect in 6-hydroxydopamine-induced model of pd in rat. materials and ...

Background and Objective: Parkinson's disease (PD) is a movement disorder with debilitating symptoms. Available treatments for PD mainly include its symptomatic relief with no prevention of its progression. Due to the iron-chelating and antioxidant effect of phytic acid (PA), this study was conducted to assess its protective effect in 6-hydroxydopamine-induced model of PD in rat. Materials and ...

Journal: :journal of basic and clinical pathophysiology 2013
ladan habibi-nikakhlagh sima nasri mehrdad roghani

background and objective: parkinson’s disease (pd) is a rather common neurological disorder in elders that is due to degeneration of dopaminergic neurons within mesencephalic substantia nigra pars compacta. with regard to protective and antioxidant effect of simvastatin, this study was conducted to evaluate its neuroprotective effect in an experimental model of pd. materials and methods: in thi...

ژورنال: دانشور پزشکی 2014
روغنی, مهرداد, قینی, محمدحسین , مس کار, حسین,

Background and Objective: Parkinson's disease is a common movement disorder in elders caused by depletion of dopaminergic neurons in the substantia nigra in midbrain. Due to antioxidant and neuroprotective properties of epigallocatechin gallate (EGCG), the present study investigated its neuroprotective effect in an experimental model of Parkinson's disease. Materials and Methods: In this exp...

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