Reaction of N-phenyl-pivalohydroxamic acid with Ce(III) precursors leads to a homoleptic hydroxamate complex: Ce(IV)[(t)BuC(O)N(O)Ph]4. Electrochemical experiments indicate a significant stabilization of the Ce(IV) cation at Ep,c = -1.20 V versus SCE in the hydroxamate ligand framework. The spontaneous oxidation of Ce(III) in a hydroxamate ligand field is discussed in the context of beneficiati...

BACKGROUND AND PURPOSE Based on their ability to chelate metals, hydroxamate molecules and siderophores have been successfully used as metalloenzyme inhibitors. As the anthrax toxin lethal factor (LF) is a zinc (Zn)-metallopeptidase, an investigation of the ability of some small non-siderophore hydroxamate compounds, 5 hydroxamate-containing siderophores, and 1 catecholate siderophore was under...

Seven lines of haploid Nicotiana tabacum tissue culture selected for resistance to normally toxic levels of the glycine analog glycine hydroxamate, a competitive inhibitor of the glycine decarboxylase reaction, were investigated. The presence of glycine hydroxamate greatly increased the intracellular concentration of both glycine and alanine in wild type and resistant cell lines, suggesting tha...

l-Arginine hydroxamate inhibited the growth of various bacteria, and the inhibition was readily reversed by arginine. l-Arginine hydroxamate (10(-3)m) completely inhibited the growth of Bacillus subtilis. This inhibitory effect was prevented by 2.5 x 10(-4)ml-arginine, which was the most effective of all the natural amino acids in reversing the inhibition. l-Arginine hydroxamate-resistant mutan...

Peptide deformylase (PDF) catalyzes the removal of the formyl group from the N-terminal methionine residue in newly synthesized polypeptides, which is an essential process in bacteria. Four new inhibitors of PDF that belong to two different classes, hydroxamate/pseudopeptide compounds [PMT387 (7a) and PMT497] and reverse-hydroxamate/nonpeptide compounds [PMT1039 (15e) and PMT1067], have been de...

The structural analogue of l-serine, l-serine hydroxamate, inhibited the growth of Escherichia coli K-12. Of the other amino acid hydroxamates tested, only l-lysine hydroxamate reduced the rate of growth. Inhibition of growth by l-serine hydroxamate was rapidly reversed by the addition of l-serine to the bacterial culture or by removal of the analogue by filtration. The reversal of inhibition w...

Chemical modification of naturally occurring polysaccharide, guaran has been made by incorporating 5aminosalicylic hydroxamate moiety to improve its selectivity and capacity for heavy metal ions. 5Amino salicylic acid hydroxamate derivative of guaran (ASAH-G) was synthesized, characterized and its adsorption behavior with Fe(II), Co(II), Ni(II), Cu(II), Zn(II), Cd(II), U(VI), W(VI), Cr(VI) and ...

An unprecedented encapsulation of an exogenous sodium ion by iron(III) tris(hydroxamate)s was observed upon crystallization of an iron(III) complex with isonicotinylhydroxamic acid. The sodium cation is bound by bridging coordination of the amide oxygen atoms from two mononuclear iron(III) fac-tris(hydroxamate)s.

An efficient synthetic protocol to functionalize the cyanoacrylic acid anchoring group of commercially available MK-2 dye with a highly water-stable hydroxamate anchoring group is described. Extensive characterization of this hydroxamate-modified dye (MK-2HA) reveals that the modification does not affect its favorable optoelectronic properties. Dye-sensitized solar cells (DSSCs) prepared with t...