background: numerous evidences indicate that in some hiv-1 positive patients, the humoral and cellular immune responses are induced against hiv-1 proteins and this is inversely related to the progress of infection. objective: the aim of this study was the evaluation of the adenovectors containing hiv genes in induction of immune responses in mice. methods: the hiv-1 genes including gag p24, rev...

background: rhipicephalus ( boophilus ) annulatus tick is one of the most important ectoparasite of cattle. re­cently, several laboratories in the world have been concentrated on immunizing cattle against tick using various types of tissue extracts of ticks. the aim of this study was to evaluate the effect of immunization of cattle with tick salivary gland extract on biological parameters of ti...

Memory formation is the most important aspect of a vaccine which can guarantee long-lasting immunity and protection. The main aim of the present study was to evaluate the memory immune responses after immunization with a mini vaccine. Mice were immunized with human immunodeficiency virus-1 P24-Nef fusion peptide and then cellular and humoral immune responses were evaluated. In order to determin...

memory formation is the most important aspect of a vaccine which can guarantee long-lasting immunity and protection. the main aim of the present study was to evaluate the memory immune responses after immunization with a mini vaccine. mice were immunized with human immunodeficiency virus-1 p24-nef fusion peptide and then cellular and humoral immune responses were evaluated. in order to determin...

introduction: hepatitis c virus (hcv) infection is a major public health problem which influences about 170 million people worldwide. different types of vaccines have been designed using hcv structural proteins to control the viral infection. the core nucleocapsid protein is one of the most conserved proteins and a desirable target for hcv vaccines, especially the protein-based vaccines. in cur...

objective: several vaccines against hiv have been investigated but none has been approved as an effective hiv vaccine. an approach that could induce stronger immune response against the pathogen is utilizing a multi-epitopic vaccine. this strategy was used in the design of several vaccines and resulted in improved immune responses. materials and methods: in this study a multi-epitopic fusion p...

Background: Numerous evidences indicate that in some HIV-1 positive patients, the humoral and cellular immune responses are induced against HIV-1 proteins and this is inversely related to the progress of infection. Objective: The aim of this study was the evaluation of the Adenovectors containing HIV genes in induction of immune responses in mice. Methods: The HIV-1 genes including gag p24, rev...

Introduction: Glycoprotein B (gB) is the major antigen for induction of humoral responses against human cytomegalovirus (HCMV) making it an attractive candidate for immune prophylaxis. In the present study, the humoral immune response of BALB/c mice to a truncated HCMV gB protein fused with GFP was evaluated. Methods: The truncated gB coding sequence was synthesized and cloned in pEGFPN1 eukary...

the aim followed in the present study was an evaluation of the adaptive immune traits (cellular and humoral) of both males and females in iranian commercial vs azarbayijan native fowls. information obtained from cellular and humoral responses of 49 birds of arian broiler line. 79 azarbayijan native birds were made used of. total antibody titration, immunoglobulin y titration (igy), and immunogl...

Background: Major histocompatibility complex (MHC) is one of the best characterized genetic regions controlling immune responses against vaccines. Identifying the association between MHC haplotypes and improved immune responses would be useful in genetic breeding strategies in animals. OBJECTIVES: MHC class II B genetic diversity and its association with humoral immune responses against Newcast...