despite diagnostic, preventive and therapeutic advances, growing incidence of cancer and high rate of mortality among patients affected by specific cancer types indicate current clinical measures are not ideally useful in eradicating cancer. chemoresistance and subsequent disease relapse are believed to be mainly driven by the cell-molecular heterogeneity of human tumors that necessitates perso...

placental site trophoblastic tumor (pstt) is the rare variant of gestational trophoblastic diseases (gtd), which differs histologically and immunologically from gtd. diagnosis of pstt is often difficult and delayed. in most cases, diagnosis is not possible until the surgery is performed. the most therapeutic choice is hysterectomy and it is usually successful. here we report two cases of pstt.

EBV-carrying human cell lines, depending on whether the cells are derived from Burkitt's lymphoma (BL) tumor biopsies or transformed by EBV in vitro, have different growth properties in vitro. In contrast, there are no clear differences between tamarin tumor lines and tamarin LCLs in vitro. Both types of tamarin cell lines could grow in agarose and formed colonies unlike human LCLs, althoug...

ebv-carrying human cell lines, depending on whether the cells are derived from burkitt's lymphoma (bl) tumor biopsies or transformed by ebv in vitro, have different growth properties in vitro. in contrast, there are no clear differences between tamarin tumor lines and tamarin lcls in vitro. both types of tamarin cell lines could grow in agarose and formed colonies unlike human lcls, althou...

objective: micrornas (mirnas) are a new class of non-coding rnas involved in regulating various biological processes including proliferation, differentiation, and apoptosis, among others. alterations in mirna expression are reported in several human cancers, which suggests their potential roles in tumor initiation and progression. members of the mir-302 cluster are highly expressed in embryonic...

Despite diagnostic, preventive and therapeutic advances, growing incidence of cancer and high rate of mortality among patients affected by specific cancer types indicate current clinical measures are not ideally useful in eradicating cancer. Chemoresistance and subsequent disease relapse are believed to be mainly driven by the cell-molecular heterogeneity of human tumors that necessitates perso...

Objective(s): Lung cancer is the main leading cause of cancer death worldwide. Angiogenesis is the main step in proliferation and spreading of tumor cells. Targeting vascular endothelial growth factor (VEGF) is an effective approach for inhibition of cancer angiogenesis. Nanobodies (NBs) are a novel class of antibodies derived from the camel. Unique characteristics of Nbs like their small size ...

Abstract: Background  and  Aims:  Huh-7  is  a  cell  line  that  was  derived  from  a  liver  tumor  of  a  Japanese  man.  Hepatocellular  carcinoma  (HCC)  is  considered  as  a  primary  liver  cancer.  Highly  resistant  tumor  to  treatment  which  causes  the  death  of  many  patients  annually.  Thus,  targeting  the  cancer  cells  by  using  a  new  method  could  be  effective  in...

Introduction: It has been reported that platelets can eradicate tumor cells in vitro, although the mechanism of this effect has not been determined. The effect of platelets on the induction of apoptosis in tumor cells is largely unknown. Materials and methods: To investigate this effect, two human hematologic cell lines, K562 and Daudi, were independently faced with unstimulated and thromb...