Background and Aims: Rotaviruses are one of the main causative agents of acute viral gastroenteritis in both young human and animals. Several methods have been used for diagnosis of rotavirus infection. Most of these methods are not easily available in Iran. Methods: In our study attempt was made to develop a method which could replace the commercially imported Kit. Rota virus was purified and...

A series of reassortants was isolated from coinfection of cell cultures with a wild-type animal rotavirus and a "noncultivatable" human rotavirus. Wild-type bovine rotavirus (UK strain) was reassorted with human rotavirus strains D, DS-1, and P; wild-type rhesus rotavirus was reassorted with human rotavirus strains D and DS-1. The D, DS-1, and P strains represent human rotavirus serotypes 1, 2,...

Background and Aims: One of the major causes of acute diarrhea in children during the cold season in Iran is infection by rotavirus. Children infected with rotavirus often require hospitalization. Several studies on human and animals have shown that enterotoxigenic Escherichia.coli and rotavirus are the most common coinfection causing diarrhea. There are other reports indicating occurrence of r...

Background and Aims: In humans the group A rotaviruses are associated with endemic diarrhea in children under the age of 5, leading to approximately 800,000 deaths every year. Introduction of rotavirus vaccines into childhood immunization programs can contribute to substantial reduction in mortality from rotavirus gastroenteritis in developing countries and virtually eliminating hospitalization...

background human rotavirus is a significant cause of severe gastroenteritis in infants and young children worldwide. in recent years, rotavirus genotyping by rt-pcr has provided valuable information about the diversity of rotaviruses circulating worldwide. the purpose of the present study is to monitor the prevalence of the different g types of rotaviruses circulating in shiraz, southern iran a...

By the plaque reduction neutralization test, the CU-1 strain of canine rotavirus was similar, if not identical, to three strains (no. 14, no. 15, and P) of the tentatively designated third human rotavirus serotype. In addition, strain CU-1 demonstrated a one-way antigenic relationship with two other strains (M and B) of the third human rotavirus serotype. The CU-1 strain of canine rotavirus hem...

background and aims: one of the major causes of acute diarrhea in children during the cold season in iran is infection by rotavirus. children infected with rotavirus often require hospitalization. several studies on human and animals have shown that enterotoxigenic escherichia.coli and rotavirus are the most common coinfection causing diarrhea. there are other reports indicating occurrence of r...

or postnatally with human rotavirus D (serotype 1) were tested by plaque reduction neutralization assay for antibody to bovine rotavirus and to three serotypes of human rotavirus. Homologous antibody developed in all animals, but antibody to heterologous rotaviruses developed mainly in animals exposed in utero to bovine rotavirus. The development of heterologous antibody may explain the immunol...

A human stool filtrate containing rotavirus which was administered orally to gnotobiotic lambs caused diarrhea, virus excretion, development of antibodies to rotavirus, and pathological changes in the villi of the small intestine. Thus, lambs may serve as experimental animals for the study of human rotavirus infections. This model system was used to study passive protection. Human immunoglobuli...

background and aims: in humans the group a rotaviruses are associated with endemic diarrhea in children under the age of 5, leading to approximately 800,000 deaths every year. introduction of rotavirus vaccines into childhood immunization programs can contribute to substantial reduction in mortality from rotavirus gastroenteritis in developing countries and virtually eliminating hospitalization...