background: this study was undertaken to establish the characterization of cultured oral mucosal epithelium and introducing them as an alternative source for reconstruction of ocular surface disease. methods: human oral epithelial cells were cultured on simple media (dmem/hf12) as control and co-cultured on mitomycin c-treated 3t3 feeder layer, on the amniotic membrane (am) without nitrocellulo...

objective: tooth loss is a common problem and since current tooth replacement methods cannot counter balance with biological tooth structures, regenerating natural tooth structures has become an ideal goal. a challenging problem in tooth regeneration is to find a proper clinically feasible cell to seed.this study was designed to investigate the odontogenic potential of human bone marrow mesench...

Background: This study was undertaken to establish the characterization of cultured oral mucosal epithelium and introducing them as an alternative source for reconstruction of ocular surface disease. Methods: Human oral epithelial cells were cultured on simple media (DMEM/HF12) as control and co-cultured on mitomycin C-treated 3T3 feeder layer, on the amniotic membrane (AM) without nitrocellulo...

Development of effective in vitro human lip models, specific to the vermilion epithelium, has not progressed as much that skin and oral mucosa/gingiva models vitro. Our histologic examination demonstrated a Japanese macaque (male, 7 years 9 months old) had distinct from adjacent mucosa, resembling histological characteristics lip. Therefore, this study, we examined gene expression profile three...

introduction: heterotopic gastrointestinal cyst of the oral cavity is an extremely rare lesion with fewer than 40 cases reported in the english literature. it usually involves the soft tissue covering the floor of the mouth and the tongue. lining of this lesion resembles gastric or intestinal mucosa. case report: in this report we describe the lesion in two boys and discuss their pathogenesis.

background: keratinocyte growth factor (kgf) is a potent epithelial mitogen that acts by binding the kgf receptors (kgfrs) expressed on epithelial cells and regulates proliferation and differentiation. the objective of this study was to investigate the expression of kgf in the epithelium in oral precancer. materials and methods: archival tissues of oral submucous fibrosis (smf) and leukoplakia ...

Aberrant expression of TGF-alpha is associated with human malignant oral epithelium. Experiments were initiated to determine the cellular sources of transforming growth factor-alpha (TGF-alpha) in human oral cancer. Ten freshly resected human oral cancers and four specimens of normal human oral epithelium were studied by in situ hybridization and immunohistochemistry. Tissues were probed with 3...

soft tissue-implant interface is an important anatomical feature contributing to the long-term success of dental implants. based on the available evidence, different factors may influence biological width around implants including the surgical technique, implant loading, implant surface properties, abutment materials, implant position, and width of the peri-implant mucosa. the purpose of the pr...