background: premature chromosome condensation (pcc) is a method for interphase chromosome analysis in biodosimetry. this study was performed to verify the usefulness of pcc induced by calyculin a in human peripheral blood lymphocytes (pbl) for biological dosimetry and possible construction of dose-response curve. materials and methods: peripheral blood was obtained from a healthy donor and expo...

Perfluorinated compounds (PFCs) such as perfluorooctanesulfonate (PFOS) are stable chemicals that accumulate in biological matrix. Toxicity of these compounds including immunotoxicity has been demonstrated in experimental models and wildlife. Although limited number of studies examined the effects of PFOS on human lymphocytes but so far no research has investigated the complete mechanisms of PF...

background: modulation of the immune response is an important strategy by which establish­ment and growth of hydatid cyst in the internal organs of human is warranted. induction of apop­tosis in the lymphocytes might be a considerable component. this study was designed to evaluate apoptotic impact of hydatid fluid (hf) on human lymphocytes. methods: human lymphocytes were treated with hydatid f...

Perfluorinated compounds (PFCs) such as perfluorooctanesulfonate (PFOS) are stable chemicals that accumulate in biological matrix. Toxicity of these compounds including immunotoxicity has been demonstrated in experimental models and wildlife. Although limited number of studies examined the effects of PFOS on human lymphocytes but so far no research has investigated the complete mechanisms of PF...

background: lymphocyte-dicentric assay is the most generally accepted method for biological dosimetry of overexposed individuals. in this study, the frequency of unstable chromosome aberration in blood lymphocytes was used to estimate radiation dose received by individuals. evaluation of dose using a calibration curve produced elsewhere may have a significant uncertainty therefore, experiments ...

background helicobacter pylori (h. pylori) is recognized as the causative agent of peptic and duodenal ulcers, gastric adenocarcinoma, and low-grade mucosa-associated lymphoid tissue (malt) lymphoma . in the present study, we investigate the genotoxic damage of lysates of h. pylori in human b lymphocytes. materials and methodsâ  human b lymphocytes were treated with 0, 10, 20, and 30 âµg/ l of ...

application of nuclear magnetic resonance imaging (nmri) as a non-invasive and accurate imaging procedure has been widely used in recent years. meanwhile, the biological effects of magnetic fields of several tesla (t) and high energy radiofrequency (rf) is not fully known yet. because of controversy over this issue, the present research has been carried out in order to verify the effects of mag...

BACKGROUNDS: Seminoma is frequently observed in human and canine testes especially in cryptorchids. Canine and human seminomas are typically associated with leukocytic infiltration. OBJECTIVES: We aimed to identify the type of lymphocytes that infiltrate to seminomas. METHODS: Tumor infiltrating lymphocytes were evaluated by immunohistological techniques in 5 dogs with diffuse seminoma. Routine...

normal 0 false false false en-us x-none ar-sa background: more than 100,000 iranian veterans and civilians still suffer from various long-term complications due to their exposure to sulfur mustard (sm) during the iran–iraq war in 1983–88. the aim of the study was to investigate dna damage of sm in veterans who were exposed to sm, 23–27 years prior to this study. materials and methods: blood sam...

objective(s):  chlorpyrifos (cp) is a broad-spectrum organophosphorus pesticide used extensively in agricultural and domestic pest control, accounting for 50% of the global insecticidal use. in the present study, protective effects of two selenium-enriched strong antioxidative medicines imod and angipars were examined in human lymphocytes treated with cp in vitro. materials and methods: isolate...