background: ferritin is an iron storage protein, which plays a key role in iron metabolism. measurement of ferritin level in serum is one of the most useful indicators of iron status and also a sensitive measurement of iron deficiency. monoclonal antibodies may be useful as a tool in various aspects of ferritin investigations. in this paper, the production of a murine monoclonal antibody (mab) ...

ferritin is a macromolecule and is responsible for the long term iron storage function in human serum and plasma. recent studies have highlighted the role of cell phone exposure on central nervous system, immune function and reproduction. the aim of this study was to investigate whether the human serum ferritin level could be interfered by the exposure to the 900 mhz gsm cell phones. fifty huma...

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Ferritin is the intracellular iron storage protein. Tissue ferritin stores are markedly increased in hemochromatosis, a disease of iron overload that has been linked to chromosome 6. In order to provide further information concerning the genetics of ferritin synthesis and to determine if the structural gene for ferritin was on chromosome 6, studies were performed to identify the human chromosom...

reply to the letter sent by prof. viroj wiwanitkit entitled “radiofrequency radiation and human ferritin”   authors of the article entitled “effects of radiofrequency radiation on human ferritin: an in-vitro enzymun assay” [1] would like to express their satisfactions, since the manuscript have been accessed and used as an element of reflection by a renowned researchers such as prof. wiwanitkit...

BACKGROUND Ferritin is an iron storage protein, which plays a key role in iron metabolism. Measurement of ferritin level in serum is one of the most useful indicators of iron status and also a sensitive measurement of iron deficiency. Monoclonal antibodies may be useful as a tool in various aspects of ferritin investigations. In this paper, the production of a murine monoclonal antibody (mAb) a...

Ferritin has been purified from normal full-term human placentae and its antigenic and molecular characteristics compared with adult liver ferritin. Placental ferritin is composed predominantly of a single subunit type, co-migrating with a liver ferritin standard on sodium dodecyl sulphate/polyacrylamide-gel electrophoresis. Comparison of dose-response curves in an immunoradiometric assay indic...

Anti-ferritin autoantibodies are found in many animals. Human ferritin-binding proteins (FBPs) were partially purified from human serum by ion-exchange chromatography and immobilized metal affinity chromatography with Zn. Crude FBPs were immunocoprecipitated with canine liver ferritin followed by the addition of anti-ferritin antibodies. Immunoglobulins in the immunocoprecipitate were detected ...

Hepatic iron overload causes lipocyte activation with resultant fibrogenesis. This study examines whether rat lipocytes express ferritin receptors, which could be involved in paracellular iron movement and in cellular regulation. Lipocytes from normal rat liver were cultured on plastic and incubated with 125I-labeled rat liver ferritin (RLF) +/- a 100-fold excess of either unlabeled RLF or huma...

We compared three serum ferritin radioimmunoassay kits and one noncommercial RIA for ferritin quantitation, with regression analysis of results for sera from 35 ostensibly healthy subjects. There was a good correlation (p less than 0.001) between these various RIAs, but the slope of the regression line varied widely, most probably because of lack of standardization of the serum ferritin assay. ...